To determine the geotechnical properties of anisotropic rocks, five types of various metamorphic rocks were selected from different parts of Hamedan province, west of Iran. These samples were subjected to mineralogical, physical, and mechanical laboratory tests and their behaviors were obtained at different angles between loading axis and foliation planes (anisotropy angle or β; 0°, 15°, 30°, 45°, 60°, 75°, and 90°). Based on the results, type, and amount of contained minerals have influence on the physical and mechanical properties of anisotropic tested rocks. Also, the Schmidt hardness (Hs) and mechanical properties of the samples, such as point load index (Is(50)) and Brazilian tensile strength (BTS) are affected by the anisotropy angle (β). In this research, the empirical equations relating different studied properties of the anisotropic rocks were obtained. In this regard, new equations were proposed for calculating point load index (Is(50)) and Brazilian tensile strength (BTS) in different angles of anisotropy (β).