Studies conducted in a forest nursery (Moscow region, Russia) have established the following. Seeds, additionally sorted by size and weight, should be used for the cultivation of large spruce seedlings (Picea abies (L.) H. Karst.). Lightweight seeds must be removed. Only heavy and medium weight seeds should be used for sowing. When sowing, the seeds must be distributed uniformly in the sowing line with the same distance between them. The rate of sowing of spruce seeds should ensure the optimal plant density in the sowing line in the amount of 20-30 pieces per meter. Horizontal pruning of spruce seedling roots must be carried out at a depth of 12-15 cm at the age of three in the second half of July. This enables to form a fibrous root system and developed crown of plants. Innovative technology of cultivation of large spruce seedlings in the sowing section of the nursery enables to get planting material which is similar to transplants.