Saponins of plants of wild Panax species (Araliaceae), collected at Chame and Ghorapani in central Nepal and designated as a subspecies or a variety of P. pseudo-ginseng, were investigated. From rhizomes of the specimen collected at Chame, the known dammarane-saponins, ginsenosides-Rg1 (1), -Re (2), -Rb1 (4), -Rb3 (5), -Rd (6) and gypenoside XVII (7) were isolated together with two new saponins, 24(S)-pseudo-ginsenoside F11 (3) and monoacetyl-ginsenoside-Rd (8; named pseudo-ginsenoside-RC1). From rhizomes of the specimen collected at Ghorapanai, 1-7, notogin-senoside-R1 (11), quinquenoside-R1 (12), majonoside-R2 (13) and malonyl-ginsenoside-Rb1 (14)were isolated, No saponin of oleanolic acid (16) was detected in either of the specimens. The specimens of the present study have a horizontally elongated rhizome, being morphologically similar to the Panax spp. which distributed from Bhutan in the Eastern Himalaya (P. pseudo-ginseng subsp. himalaicus) to Japan through the South-West province of China, the rhizomes of which contain a large amount of the common saponins of 16 along with the dammarane saponins. It is chemotaxonomically and pharmacognostically significant that the saponin composition of the specimens of the present study is evidently different from that of these plants, being rather similar to that of roots of P. ginseng, P. quinquefolium and P. notoginseng whose big carrot-like roots contain a number of physiologically active dammarane saponins with only trace levels or none of the saponin of 16.