Received 20 November 2014Received in revised form23 December 201418 February 2015Accepted 24 February 2015The purpose of this study is to examine the possibility of science education using Korean TSK(Traditional scientific knowledge). In this study, we have developed five Korean TSK units including science concepts, historical knowledge and cultural experience and applied them to 10th graders. The five units are as follows: (1) Calendars(western and eastern), (2) Our traditional sundial, Angbuilgu, (3) A great scientist in the King Sejong Era, (4) Data interpretation of ancient record of natural phenomenon in Korea, and (5) Gyeongbokgung Palace. The analyses included a pre- and post test of students' perception, classroom observation, students' activity sheets, and interview. The results show that the students' perception of Korean TSK has changed toward recognizing the value of Korean TSK as a kind of natural science. They expressed their expectation of Korean TSK in scientific, practical, and emotional perspectives, wherein some students thought the practical and emotional perspectives of Korean TSK as non-scientific characteristics. Students showed five types of worldview about the relationship between Korean TSK and WMS(western modern science). Most students favored and cherished the Korean TSK but at the same time, they were confused about its scientific value. The results support the rethinking of the meaning of science and what students learn in school. We should consider how we teach the Korean TSK to students. It is important that a profound research of the Korean TSK should be continued to make our science education varied.