Abstract In this article, the integrity of the seismic catalog obtained (1970–2014, M > 2.8) was verified according to the Gutenberg–Richter relation, the appropriate minimum magnitude was determined, and the whole region was divided into five areas according to the geological structure background of the whole research object and the trend of the historical seismic zone. We applied multifractal analysis in each partition. The results showed that although in different geological backgrounds, before major earthquakes, the earthquake time series information dimension had different degrees of growth, and the parameter after the flame had different degrees of decline. To a certain extent, this reflected the seismic energy accumulation and release process. In addition, the variation of fractal parameters in scale-free regions of time series and spatial distribution series also indicated that these two kinds of sequences in different regions show the characteristics of a multifractal structure rather than a single and uniform fractal structure.