We report the design and implementation of a one-dimensional guided-mode resonance filter (1D-GMRF) aiming to achieve polarization insensitivity at conical mounting. (The incident plane is aligned neither perpendicularly nor parallelly to the grating bars.) The design guideline indicates that, at conical mounting, polarization insensitivity of the 1D-GMRF can be achieved by optimizing the grating parameters to excite the fundamental TE and the fundamental TM waveguide modes simultaneously. Moreover, it is revealed that, at conical mounting, the polarization-insensitive GMR position in the angle-resolved resonance spectra is azimuthal angle ϕ-dependent. The experimental results demonstrate that polarization insensitivity of the fabricated 1D-GMRF occurs at the resonance wavelength of ∼673 nm for the conical mounting of azimuthal angle ϕ≈30° and incident angle θ≈11.2°, which agree with the simulated results.