The paleobiogeographic affinity of fusulinids in the Lhasa Block remains contentious, despite its significance for deciphering the complex Paleozoic history of the Tibetan Plateau. Our new collection from the Lhunzhub area and literature data recently accumulated necessitate an up-to-date overview of the Middle Permian fusulinids in this block from both taxonomic and paleobiogeographic perspectives. Systematic identification reveals Lepidolina multiseptata multiseptata, Colania ozawai, Verbeekina cf. tenuispira, V. americana etc., indicative of a Midian age, in the new materials from the Luobadui Formation. Overall, the Middle Permian fusulinids of this block could be distinguished into two types: 1) characterized by verbeekinids and neoschwagerinids; 2) dominated by Nankinella and Chusenella . Furthermore, these fusulinids as a whole were compared, at the generic rank, with their counterparts from other Gondwana-derived blocks, as well as Cathaysian South China, both qualitatively and quantitatively (cluster analysis and principal ordination analysis). Results show that these fusulinids of the Lhasa Block, is closely affiliated with those of the South Qiangtang, both of which paleobiogeographically belong to the Cimmerian Province, especially based on the occurrence of Rugososchwagerina ( Xiaoxinzhaiella ) and smaller foraminifer Shanita . Meanwhile, the Lhasa Block also bears resemblance with Cathaysian South China by sharing some genera of verbeekinids and neoschwagerinids, including the Lepidolina which more commonly occurs in the eastern Tethys and Panthalassa. It is remarkable that the Lhasa Block accommodates more diversified Middle Permian fusulinids than the eastern Cimmerian blocks do, given its lacking Early Permian fusulinids. Such contrast between the Early and Middle Permian fusulinids reflects considerable climatic amelioration of the Lhasa Block, which is interpreted to mainly result from its rifting from Gondwana before the Guadalupian time and northward drifting afterwards. The Lhasa Block was possibly located near to the South Qiantang Block, and at lower paleolatitudes than the eastern Cimmerian blocks during the Middle Permian. • Two types of Mid-Permian fusulinid faunas in Lhasa Block, Nankinella- dominated or not. • Lepidolina , more commonly in eastern Tethys and Panthalassa, confirmed in Lhasa Block. • It is part of Cimmerian Province due to endemic taxa and less diversity than S. China . • It might be near S Qiantang and at lower palaeolatitudes than E. Cimmeriarn blocks. • Our study supports that it rifted from the Gondwana margin before the Guadalupian.