We consider a generalized (3+1)-dimensional nonlinear Schrödinger with cubic-quintic nonlinear and self-frequency shift and self-steepening terms. We disrupt the plane wave to study the stability of the wave in this media. We examine how various factors—such as the amplitude of the plane wave, cubic and quintic nonlinear terms, self-steepening, and self-frequency shift—affect the modulational instability (MI). Our findings reveal that the amplitude of the plane wave and the quintic nonlinear term can expand the MI bands and increase the amplitude of the MI growth rate. Conversely, the self-steepening and self-frequency shift terms exert opposite effects, narrowing the MI bands and reducing the amplitude of the MI growth rate. We investigate the existence of modulated chirped rational and polynomial Jacobi elliptic function solutions and chirped optical solitons.