This paper investigates the energy absorption capacities of selected cellular topologies under quasi-static loading conditions. Twenty topologies with nearly identical relative densities belonging to 4 groups were examined: honeycomb, re-entrant, bioinspired and chiral. The topologies were modeled using an experimentally validated numerical ABSplus model and subsequently subjected to in-plane uniaxial compression tests. The findings revealed the topologies with the most favorable energy absorption parameters and the main deformation mechanisms. The topologies were classified by mechanism, and a parametric study of basic material properties, namely modulus of elasticity, yield stress, and ductility, was performed for a representative topology from each mechanism. The results indicated that the honeycomb group topologies were characterized by the largest average absorbed energy, and yield stress was found to have the greatest impact on energy absorption efficiency regardless of the main deformation mechanism.