Group U3 Research Articles

A New Alternative Nutritional Source Hawthorn Vinegar: How It Interacts with Protein, Glucose and GLP-1.

(1) Background: There is a balance between nutrition, glycemic control, and immune response. Their roles in physiological mechanisms are essential for maintaining life quality. This study aimed to evaluate hawthorn vinegar's metabolic effects, and describe its possible mechanism. We also pointed out several vinegar production methods to clarify the antioxidant features. (2) Methods: In the study, three vinegar techniques were applied to vinegar: traditional production of hawthorn vinegar (N), thermal pasteurization (P), and ultrasound method (U). Thirty-two female adult Wistar albino rats were randomly separated into four groups: Control, N1 (regular vinegar; 1 mL/kg bw), P1 (pasteurized vinegar; 1 mL/kg bw), and U1(ultrasound treated vinegar; 1 mL/kg bw). Vinegar was administered by oral gavage daily for 45 days. Initial and final weights, the percentage changes of body weight gains, and Gamma-Glutamyl Transferase (GGT) values of plasma and liver were measured. The total protein, globulin, and albumin values of plasma, liver, and intestinal tissue were determined. In addition, plasma glucagon-like peptide-1 (GLP-1) and glucose concentrations were evaluated. (3) Results: There was a statistical increase in total intestinal protein value and an increasing tendency in total protein in plasma and liver in group U1 compared to group Control. However, the GGT concentrations in plasma and liver were slightly lower in group U1 than in group Control. In addition, there were significant increases in plasma GLP-1 values in all experimental groups compared to the Control group (p: 0.015; 576.80 ± 56.06, 773.10 ± 28.92, 700.70 ± 17.05 and 735.00 ± 40.70; respectively groups control, N1, P1, and U1). Also, liver GLP-1 concentrations in groups P1 and U1 were higher than in group Control (p: 0.005; 968.00 ± 25.54, 1176 ± 17.54 and 1174.00 ± 44.06, respectively groups control, P1 and U1). On the other hand, significant decreases were found in plasma glucose concentrations in groups N1 and U1 as to the Control group (p: 0.02; Control: 189.90 ± 15.22, N1: 133.10 ± 7.32 and U1: 142.30 ± 4.14). Besides, liver glucose levels were lower in all experimental groups than in group Control statistically (p: 0.010; 53.47 ± 0.97, 37.99 ± 1.46, 44.52 ± 4.05 and 44.57 ± 2.39, respectively groups control, N1, P1, and U1). (4) Conclusions: The findings suggest that hawthorn vinegar can balance normal physiological conditions via intestinal health, protein profiles, and glycemic control. Additionally, ultrasound application of vinegar may improve the ability of hawthorn vinegar, and have positive effects on general health.

A Spectroscopic Description of Asymmetric Isotopologues of CO2.

A polyad-conserving algebraic model applied to vibrational excitations of asymmetric isotopologues of CO2 is presented. First, the problem of vibrational excitations is studied by taking into account only the minimum subspace of states to characterize the Fermi interaction. This analysis allows an estimation of the force constants as well as the feasibility of describing the system in a local mode scheme, in terms of SU(2) operators associated with Morse ladder operators for the stretches. This description together with the algebraic U(3) for the bends establishes the dynamical group SU1(2) × U(3) × SU2(2) for a series of isotopologues. Six isotopologues are considered, namely, 16O12C18O, 16O12C17O, 16O13C18O, 16O13C17O, 17O13C18O, and 17O12C18O in their electronic ground states. For isotopologues 16O12C18O, 16O12C17O, 17O12C18O, and 16O13C18O, the vibrational description was carried out using a Hamiltonian involving 14 parameters. For this series of isotopologues with a number of energy terms 90, 57, 42, and 40, the deviations obtained were rms = 0.15, 0.10, 0.06, and 0.07 cm-1, respectively. For 16O13C17O, with 28 experimental energies and involving 13 parameters, the deviation was rms = 0.05 cm-1, while for 17O13C18O, a different strategy was proposed since only 12 experimental energy levels. In all cases, the polyad scheme P212 = 2(ν1 + ν3) + ν2 was considered. In addition, a new criterion of locality/normality degree is proposed, embracing the case of molecules with normal mode behavior, in particular, the isotopologues of CO2.

New evidence of the azimuthal alignment of quasars spin vector in the LQG U1.28, U1.27, U1.11, cosmologically explained

There has been observational evidence about spin axes of quasars in large quasar groups correlated over hundreds of Mpc. This is seen in the radio spectrum as well as in the optical range. There is not yet a satisfactory explanation of this “spooky” alignment. This alignment cannot be explained by mutual interaction at the time that quasars manifest themselves optically. A cosmological explanation could be possible in the formation of superconducting vortices (cosmic strings) in the early universe, just after the symmetry-breaking phase of the universe. We gathered from the NASA/IPAC and SIMBAD extragalactic databases the right ascension, declination, inclination, position angle and eccentricity of the host galaxies of three large quasar groups to obtain the azimuthal and polar angle of the spin vectors. The alignment of the azimuthal angle of the spin vectors of quasars in their host galaxy is confirmed in the large quasar group U1.27 and compared with two other groups in the vicinity, i.e., U1.11 and U1.28, investigated by Clowes (2013). It is well possible that the azimuthal angle alignment fits the predicted azimuthal angle dependency in the theoretical model of the formation of general relativistic superconducting vortices, where the initial axial symmetry is broken just after the symmetry breaking of the scalar-gauge field.

Fusion systems on a Sylow p-subgroup of SU4(p)

We determine, for p odd, all saturated fusion systems F on a Sylow p-subgroup S of the unitary group SU4(p) and we prove that they are all realizable by finite groups. In particular, we prove that S does not support any exotic fusion systems.

A INTERPRETAÇÃO DE UMA ESTROFE DA CANÇÃO “BREATHE”, DO U2, COMO UMA EXPERIÊNCIA RELIGIOSA E EM BREVE DIREÇÃO À DOUTRINA ESPÍRITA

The study aims to consider one of the stanzas of the song “Breathe”, from the Irish rock group U2, and, overcoming the simple delight and the commonly visible in the music pop scene, make out an analysis and interpretation according to the Spiritist doctrine, especially in one of its fundamentals: the reincarnation.

The effects of adding fluorescent carbon nanoparticles on various mechanical properties of denture liners.

The aim of this in vitro study was to evaluate the effects of incorporating fluorescent carbon nanoparticles (FCNs) on the hardness, tear, and tensile bond strength of an acrylic-based tissue conditioner and a silicone-based soft denture liner. FCNs added to an acrylic-based tissue conditioner (Viscogel, Dentsply; Group V) and a silicone-based soft denture liner (Ufigel P, Voco; Group U) were divided into subgroups according to the concentrations (Group 0: no water, Group 1: with only water, Group 2: 0.5% FCNs, Group 3: 1% FCNs and Group 4: 10% FCNs) (n=10/per group). Shore A hardness, tear, and tensile bond strength tests were performed. Significant decreases occurred in Groups U2, U3, and U4 compared to the control groups (Groups U0 and U1) in the tear and tensile bond strength test parameters (p<0.025). However, in both types of the tested materials, there were no statistically significant differences among the shore A hardness test results (p>0.025).

Approximate Solutions to the Klein-Fock-Gordon Equation for the Sum of Coulomb and Ring-Shaped-Like Potentials

We consider the quantum mechanical problem of the motion of a spinless charged relativistic particle with mass M, described by the Klein-Fock-Gordon equation with equal scalar Sr→ and vector Vr→ Coulomb plus ring-shaped potentials. It is shown that the system under consideration has both a discrete at E&lt;Mc2 and a continuous at E&gt;Mc2 energy spectra. We find the analytical expressions for the corresponding complete wave functions. A dynamical symmetry group SU1,1 for the radial wave equation of motion is constructed. The algebra of generators of this group makes it possible to find energy spectra in a purely algebraic way. It is also shown that relativistic expressions for wave functions, energy spectra, and group generators in the limit c⟶∞ go over into the corresponding expressions for the nonrelativistic problem.

McKay Centralizer Algebras

For a finite subgroup G of the special unitary group SU2, we study the centralizer algebra Zk(G) = EndG(V⊗k) of G acting on the k-fold tensor product of its defining representation V = C2. The McKay corre- spondence relates the representation theory of these groups to an associated affine Dynkin diagram, and we use this connection to study the structure and representation theory of Zk(G) via the combinatorics of the Dynkin diagram. When G equals the binary tetrahedral, octahedral, or icosahedral group, we exhibit remarkable connections between Zk (G) and the Martin-Jones set partition algebras.

Molecular characterization of lternaria solani isolates on tomato plant Lycopersicum esculentum Mill

Early blight disease causes severe damage to the foliar part of solanaceous crops including tomato. Fifteen isolates (12 from tomato, 2 from potato, 1 from pepper) were collected from different sources in Tripoli. Field and laboratory studies were conducted to determine cultural behaviour on PDA medium, morphological, pathogenic and molecular variation between isolates tested. Colonies of isolates revealed variation in their cultural behaviour on PDA medium ranging from cottony to appressed growth, with colour ranging between light to dark olivaceous. The pigments released by the isolates changed the medium colour to grey or brown. Morphological studies of the fungal isolates exhibited short conidiophores bearing a single or chains of paired conidia. This study revealed a significant variation in conidial size for the isolates tested ranging from 23.45 to 46.90 x 7.70 to 14.00 µm. Pathogenicity testes on fruits, plants, and detached leaves of tomato indicated a high significant variation between isolates tested ranging from highly to moderate or weak pathogenic. Genetic diversity of A. solani isolates using RAPD-PCR with oligonuclotide primers revealed significant differences in the appearance of polymorphic and monomorphic banding patterns. Three primers (OPA-07, OPA-09, OPJ-09) out of ten were able to determine the genetic fingerprints of tested isolates. Cluster analysis of RAPD-PCR products showed that primer OPA-07 was able to classify the isolates into five groups: group A (TF4,TF7, TL1, TL3), group B (TF1,TF3, TF8, PEF), group C (TF5, TF6, TF9, POL1, POL2), whereas the remaining two isolates TL2 and TF2 were unique in their patterns and were designated as group U1 and U2 respectively. Primer OPA-09 revealed four distinct genetic groups designated as: group A (TF4, TF6, TF7, TF8, TL2), group B (POL1, TL3, TF3), group C (TF5, POL2) and group D (TL1, TF1, TF2, TF9, PEF). However primer OPJ-09 was able to split the isolates tested into four distinct clusters: group A (TF1, TF7, TL3, PEF), group B (TF3, TF8, POL2), group C (TF2, TF6, TF9, TL2) and group D (TF4, TF5). The results of RAPD-PCR demonstrate existence of considerable variation in molecular characteristics of A. solan iisolates. Accordingly these isolates were classified into different groups and unique patterns with no obvious association between the pattern of clustering of the isolates and their host of origin, morphological characteristics and pathogenicity.

On presentations for unitary groups

Concise presentations for groups are useful for both theoretical and computational purposes. We give short 2-generator presentations for the 3-dimensional unitary groups U3(q) and SU3(q) for q up to 11.

Fischer-Clifford Matrices and Character Table of the Maximal Subgroup (29:(L3(4)):2 of U6(2):2

The automorphism group U6(2):2 of the unitary group U6(2)≅Fi21 has a maximal subgroup G¯ of the form (29:(L3(4)):2 of order 20643840. In this paper, Fischer-Clifford theory is applied to the split extension group G¯ to construct its character table. Also, class fusion from G¯ into the parent group U6(2):2 is determined.

Cohomology of Unipotent Group Schemes

We verify that universal classes in the cohomology of GLN determine explicit cohomology classes of Frobenius kernels G(r) of various linear algebraic groups G. We consider the relationship of $\varprojlim _{r} H^{*}(U_{(r)},k)$ to the rational cohomology H*(U,k) of many unipotent algebraic groups U. The second half of this paper investigates in detail the cohomology of Frobenius kernels (U3)(r) of the Heisenberg group U3 ? GL3.

Periodic Groups Saturated with the Linear Groups of Degree 2 and the Unitary Groups of Degree 3 over Finite Fields of Odd Characteristic

Let M denote the set of the simple 3-dimensional unitary groups U3 and the simple linear groups L2 over finite fields of odd characteristic.We prove that each periodic group saturated with groups in M is locally finite and isomorphic to either U3(Q) or L2(Q) for a suitable locally finite field Q of odd characteristic.

Finding a Career after Completing a PhD.

A famous rock anthem of the 1980s by the group U2, entitled I Still Haven't Found What I'm Looking For , had been released the year before I was born. However, contrary to the song's title, I did manage to find a job. As a fresh PhD graduate, I lived the challenges and struggles that graduate students face on a daily basis. Graduate school could be one of the most stressful (but also one of the most rewarding) periods of a young adult's life. Speaking to my peers, I realize that all of them are worried about their long-term employment projections. Without a concrete plan, most of us resort to the traditional route, including 1 or 2 postdocs, in hopes for a miracle, which is usually a tenure-track academic position. But, we know that these positions are scarce and very difficult to obtain. Many of us enter graduate school as naive and ambitious students who seem ready to tackle the world's most pressing problems. Unfortunately, we usually end up with a turbulent landing. The reality is …

Periodic Groups Saturated with Finite Simple Groups of Types U 3 and L 3

Suppose that $$ \mathfrak{M} $$ is a set whose elements are simple three-dimensional unitary groups U 3(q) and linear groups L 3(q) over finite fields. We prove that a periodic group saturated with groups of $$ \mathfrak{M} $$ is locally finite and isomorphic to U 3(Q) or L 3(Q) for some locally finite field Q.

0330: Impact of extra-corporeal membrane oxygenation in high-urgency cardiac transplantation

We evaluated the use of extra-corporeal membrane oxygenation (ECMO) support as a direct bridge for heart transplantation in high-urgency (SuperUrgence 1) adult recipients. Between January 2005 and December 2012, 81 patients supported with ECMO underwent high-urgency cardiac transplantation at our Institution (group SU1 ECMO). They were compared to 131 cardiac recipients who high-urgency transplantation during the same period (group SU1 NoECMO). Forty-four patients were supported with a peripheral ECMO, while 37 patients were supported with a central ECMO. Mean duration of support before transplantation was 17±12 days. The following characteristics were significantly different between group SU1 NoECMO and group SU1 ECMO: among the recipients, age, 49 years vs. 44 years, p<0.01; age older than 50 years, 61% vs. 42%, p<0.01; waiting time >15 days, 45% vs. 16%, p<0.01; ischemic etiology, 24% vs. 40%, p=0.02; prior sternotomy, 14% vs. 59%, p<0.01; preoperative Implantable Cardioverter Defibrillator (ICD), 50% vs. 16%, p<0.01; preoperative ventilation, 6% vs. 41%, p<0.01; preoperative inotropes, 84% vs. 67%, p<0.01, glomerular filtration rate (GFR) 76 vs. 108, p<0.01. Donor characteristics were similar in both groups. The occurrence of primary graft dysfunction and one-year mortality in group SU1 NoECMO and group SU1 ECMO were 18% vs. 42%, p<0.01 and 23% vs. 28%, p=0.37. Five-year survival was 72% (group SU1 NoECMO) and 66% (SU1 ECMO), p=0.45. A period analysis of SU1 ECMO patients is resumed in Table 1. In our experience, ECMO support is a reliable option for direct bridge to heart transplantation and it resulted in satisfactory outcomes as other high-urgency transplanted patients. Abstract 0330 – Table: Period Analysis of SU1 ECMO Patients Era I (2005-2008) Era II (2009-2012) P RECIPIENT Etiology DCM 27% 53% 0,02 Central ECMO 66% 25% <0,01 Prior Sternotomy 78% 40% <0,01 Preoperative Ventilation 56% 25% <0.01 GFR 92 124 0,03 DONOR Age >50 44% 23% 0,04 RESULTS Primary Graft Failure 32% 53% 0,06 1-Year Mortality 27% 30% 0,75

2-Frobenius groups isospectral to the simple group U 3(3)

We describe the structure of a 2-Frobenius group isospectral to the finite simple group U3(3) and construct the corresponding examples.

Role of extracellular signal-regulated kinase in central amygdala on fentanyl-induced hyperalgesia in rats

Objective To investigate the role of extracellular signal-regulated kinase1/2(ERK1/2)in the central amygdala on fentanyl-induced hyperalgesia in rats. Methods Thirty-two male Sprague-Dawley rats, weighing 60–100 g, were randomly divided into 4 groups(n=8 each)using a random number table: control group(group C), fentanyl-induced hyperalgesia group(group H), U0124 group(group U1), and U0126 group(group U2). A catheter was implanted in the central amygdale.In group C, normal saline was injected subcutaneously, and 6.5 h later dimethyl sulfoxide(DMSO)was injected via the catheter.In group H, fentanyl was injected subcutaneously to induce hyperalgesia, and 6.5 h later DMSO was injected via the catheter.In group U1, hyperalgesia was induced, and 6.5 h later ERK1 inhibitor U0124 1.5 nmol was injected via the catheter.In group U2, hyperalgesia was induced, and 6.5 h later ERK1/2 inhibitor U0126 1.5 nmol was injected via the catheter.Mechanical paw withdrawal threshold(MWT)and thermal paw withdrawal threshold(TWT)were measured before fentanyl injection, at 6.5 h after injection, and at 30 min after DMSO or U0124/U0126 administration via the catheter(T0-2). After the last measurement of pain threshold, the rats were sacrificed, and the amygdala tissues were sampled for detection of the expression of phosphorylated ERK1/2(p-ERK1/2)by Western blot in groups C and H. Results Compared with group C, the MWT and TWT were significantly decreased at T1, 2in H and U1 groups, and at T1in group U2(P 0.05). Compared with group H, the MWT and TWT were significantly increased at T2 in group U2(P 0.05). Conclusion ERK2 activation in the central amygdala is involved in the development of fentanyl-induced hyperalgesia in rats. Key words: Extracellular signal-regulated kinase(ERK); Fentanyl; Hyperalgesia; Amygdala

0056: Results of cardiac transplantation according access modalities. Single centre eight years experience

We evaluated the results of cardiac transplantation according access modalities. Between 2005 and 2012, 562 patients underwent isolated cardiac transplantation, divided into five groups: patients under left ventricular assist device (group LVAD, n=27, 5%), patients under bi-ventricular assist device (group Bi-VAD, n=25, 4%), patients transplanted under ECMO (group ECMO n=90, 16%), patients transplanted according the SuperUrgence1 waiting list without ECMO (group SU1 NOECMO n=131, 23%), patients transplanted on the standard waiting list (group Liste, n=289, 53%). A comparison between the periods 2005/2008 and 2009/2012 was made for the groups LVAD+Bi-VAD, ECMO, SU NOECMO and Liste. The occurrence of primary graft dysfunction was: 26% (group LVAD), 44% (group Bi-VAD), 42% (group ECMO), 21% (group SU1 NOECMO), 26% (group Liste). The period analysis showed no change in primary graft dysfunction over the time: 33% vs 36% (group LVAD+ Bi-VAD), 50% vs. 35% (group ECMO), 23% vs. 20% (group SU1 NOECMO), 28% vs. 24% (group Liste). One-year mortality was: 15% (group LVAD), 20% (group Bi-VAD), 31% (group ECMO), 23% (group SU1 NOECMO), 28% (group Liste). Time analysis showed a 1-year mortality decrease during the 2009/ 2012 period: 10% vs 27% (group LVAD+ Bi-VAD), 29% vs. 33% (group ECMO), 17% vs. 30% (group SU1 NOECMO), 20% vs. 34% (group Liste). Three-year survival was: 81% (group LVAD), 71% (group Bi-VAD), 64% (group ECMO), 74% (group SU1 NOECMO), 66% (group Liste). Actually, stable patients on the standard waiting lists represent only half the transplantation activity. Patients transplanted under longterm circulatory support, especially LVAD, have the best results. Superurgence1 waiting list patients have good results if they not require pre-transplant ECMO support. Need for a pretransplant ECMO is associated with a higher operative mortality. Outcomes improved over the time for every group of patients.

Ulinastatin prevents acute lung injury led by liver transplantation

BackgroundLittle is known regarding the effect of ulinastatin (UTI) on acute lung injury (ALI) induced by orthotopic liver transplantation. This study aims to investigate the protective effect of UTI on ALI induced by orthotopic autologous liver transplantation (OALT) in a rat model and to explore the potential underlying mechanism. Materials and methodsRats were randomly allocated into the following four groups (n = 8 each): (i) sham control group (group sham); (ii) model group (underwent OALT) (group model); (iii) low-dose UTI-treated group (group u1), with UTI (50 U/g) administered intravenously both before the portal vein was occluded and after liver reperfusion started; and (iv) high-dose UTI-treated group (group uh), with UTI (100 U/g) given in the same way as group ul. The lung pathologic parameters, lung water content, and levels of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, malondialdehyde (MDA), superoxide dismutase (SOD) activity, RanBP-type and C3HC4-type zinc finger-containing protein 1 (RBCK1), and peroxiredoxin-2 (Prx-2) were assessed 8 h after OALT was performed. ResultsAccording to histology, there was severe damage in the lung of group model accompanied by increases in the TNF-α, IL-1β, IL-6, and MDA levels and decreases in SOD activity and the expression of RBCK1 and Prx-2. UTI treatment significantly reduced the pathologic scores, lung water content, and TNF-α, IL-1β, IL-6, and MDA levels while restoring the SOD activity and expression of RBCK1 and Prx-2. Furthermore, compared with group u1, treatment with a high dose of UTI resulted in a better protective effect on the lung when assessed by the TNF-α, IL-1β, IL-6, and MDA levels and SOD activity. ConclusionsUTI dose-dependently attenuates ALI that is induced by OALT in this rat model, which is mainly due to the suppression of the inflammatory response and oxidant stress, which may, in turn, be mediated by the upregulation of RBCK1 and Prx-2 expression.