The duration, frequency and intensity of climate change are increasing. Adaptation to climate change is oftentimes perceived as a local concern. Vulnerable groups at the margins try to find nature-based ways to cope with extreme urban climate change events with diverse direct and indirect adaptive strategies in absence of government interventions. From this study's investigative approach in Cairo, Egypt we draw results preliminary from interviews with locals and observational walks in three vulnerable areas in the same urban zone. Research revealed that adaptation can be political, demanding that locals sometimes make hard choices, especially during the absence of government intervention. Nevertheless, some of the adaptive strategies observed can be promoted as mainstream sustainable nature-based adaptation. The discussion reflects some social and economic dimensions that affect local adaptation synergies. This study hopefully contributes to the understanding of how the capacity of individual homeowners can help mitigate climate change risk through the implementation of their own physical and psychological adaptive strategies. In addition, it bears relevance not only for countries sharing similar climates, economic conditions or similar social norms, but also for general adaptation strategies that might support ecosystem-based or nature-based adaptation or tailor-made scenarios for locally applicable adaptation to climate change.