<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> This paper presents a new methodology for reliability evaluation of composite generation and transmission systems, based on nonsequential Monte Carlo simulation (MCS) and artificial neural network (ANN) concepts. ANN techniques are used to classify the operating states during the Monte Carlo sampling. A polynomial network, named Group Method Data Handling (GMDH), is used, and the states analyzed during the beginning of the simulation process are adequately selected as input data for training and test sets. Based on this procedure, a great number of <emphasis emphasistype="boldital">success</emphasis> states are classified by a simple polynomial function, given by the ANN model, providing significant reductions in the computational cost. Moreover, all types of composite reliability indices (i.e., loss of load probability, frequency, duration, and energy/power not supplied) can be assessed not only for the overall system but also for areas and buses. The proposed methodology is applied to the IEEE Reliability Test System (IEEE-RTS), to the IEEE-RTS 96, and to a configuration of the Brazilian South-Southeastern System. </para>