The unlimited usage of social media of teenagers is a pervasive problem across the world. Many researchers have found the explicable correlation between social networks and discrimination. However, the effect of social media on marginalized teenagers such as LGBTQ and disabled population is yet under-discussed. Adolescents are at a critical stage of physical and psychological growth and maturity, as well as sexual orientation. The LGBTQ+ community experiences a lot of stigmatization and discrimination, which affects their normal lives. Similarly, people with disabilities are also lagging behind in their development due to inadequate education and support. Hence, the present study aims to provide a holistic review of how social media affects adolescence’s discrimination among their LGBTQ and disabled peers. The conditions and plight of marginalized communities were first presented. Results implicate that social media could benefit marginalized group by offering a collaborative and united group in some extent. However, there are excessive amounts of long-lasting negative comments towards this population. The true mechanism and causation require further researches.