With the increasing demand of high quality infrastructure, the lack of conventional material in cities becomes the main problem. Due to this limitation in conventional material such as ordinary sand that is excavated from the river and harmful for the environment due to the reduction in ground water level, can be partially/fully replaced by M−Sand/Crushed stone rub down as an economic and ecological alternative for sustainable concrete structures. The use of M−Sand is a great effort towards sustainable enlargement in India. The life of a structure is affected by various parameters i.e. moisture content, free surface moisture (real time sample received in the lab), saturated surface dry (SSD), specific gravity, grain size analysis (to find out the sand zone), workability, water-cement ratio, impact value of aggregates etc. In this situation, while code provisions are also not available for M−Sand, a design parametric study has been conceded in the laboratory with respect to all necessary parameters for M−30 grade of concrete with different percentages of Manufactured-Sand which highly affects the design mix of concrete. In this article river or natural sand has been replaced fully and partially by M−Sand/Crushed sand likewise 0.0%, 10%, 40%, 45%, 50%, 55%, 65%, 75%, 85% & 100%. An advanced design mix procedure has been initialized here by using British codes, ACI & IS. It has been observed in the current research that most of the properties of River/Natural Sand and M−Sand/Crushed Sand are similar and it is also concluded that natural sand is able to be partially or full replaced by Manufactured sand as an economical substitute including sustainable construction material in Civil Engineering Construction era 4.0:Janpad Abhiyantriki (Civil Engineering).