The article addresses anthropogenic and geological conditions related to the development of soil subsidence in the western zone of Recife (Brazil). Over the past 50 years, human activity has intensified in areas previously affected by soft soils (clay, silt, and sandstone) resulting in subsidence due to additional loads (landfills and constructions). The duration of the settlement process can be significantly influenced by the specific characteristics of the soil composition and geological conditions of the location. This work presents, for the first time, accurate InSAR time series maps that describe the spatial pattern and temporal evolution of the settlement, as well as the correlation with the geological profile, and validation with Global Navigation Satellite System (GNSS) data. Persistent Scatterer Interferometry (PS-InSAR) was employed in the analysis of Single Look Complex (SLC) images generated by 100 ascending COSMO-SkyMed (CSK) and 65 PAZ (32 ascending, and 33 descending) from the X-band, along with 135 descending Sentinel-1 (S1) acquisitions from the C-band. These data were acquired over the period from 2011 to 2023. The occurrence of subsidence was identified in several locations within the western region, with the most significant displacement rates observed in the northern, central, and southern areas. In the northern region, the displacement rates were estimated to be approximately −20 mm/year, with the Várzea and Caxangá neighborhoods exhibiting the highest rates. In the central region, the displacement rates were estimated to be approximately −15 mm/year, with the Engenho do Meio, Cordeiro, Torrões, and San Martin neighborhoods exhibiting the highest rates. Finally, in the southern region, the displacement rates were estimated to be up to −25 mm/year, with the Caçote, Ibura, and Ipsep neighborhoods exhibiting the highest rates. Additionally, east–west movements were observed, with velocities reaching up to −7 mm/year toward the west. These movements are related to the lowering of the land. The study highlights that anthropogenic effects in the western zone of Recife contribute to the region’s vulnerability to soil subsidence.