A field study was conducted during 2013/14 cropping season with the objectives of to study the response of bread wheat to different rates of sulfur fertilizer, to study the effect of sulphur fertilization on growth and yield of bread wheat and to suggest some recommendations about the optimal rates of sulfur fertilizer application for bread wheat as well as for further sulfur research works. The treatments applied as one factor of six levels of sulphur (0, 20, 40, 60, 80 and 100 kg S ha-1. The treatments were replicated three times in a Randomized Complete Block Design. The experiment was carried out at the Kulumsa Agricultural Research Center on clay textured soil. Data were collected and statistical analysis was done on various characters of the crop. Soil Samples were also taken before and after the implementation of the experiment and chemically analyzed. The analysis of variance for the results of the study revealed among the agronomic and yield parameters of wheat; Number of Seedling, Number of Tillers per Plant, 50% of flowering date, Plant Height, spike length, Number of Spikes, Number of Seeds per spike, Total Above Ground Biomass Yield and Harvest Index were non-significant (p> 0.05) influenced by rate of S whereas Thousand Grains Weight, and grain yield were significantly (p≤0.05) affected by rates of S. Application of 60 kg S/ha increased the grain yield of wheat by 12.64%, 11.39%, 6.44% and 2.52% respectively when compared with the no S application. 60 kg/ha is recommended for vertisol at kulmsa.