Green Walnut Research Articles

Antioxidant, Keratolytic, and Hydrating Treatment for Seborrheic Keratoses.

Seborrheic keratoses (SKs) are the most common skin lesions to prompt visits to a dermatologist. Patients may be concerned about unsightly appearance, irritation, or the possibility of skin cancer. They frequently ask if there is a topical treatment for these lesions. We sought to determine an effective topical formula to improve the appearance of seborrheic keratosis and test the formula in a pilot observational study on a small number of patients. A topical mixture of antioxidants, hydrating, and keratolytic agents was applied to five SKs on four patients in a private dermatology clinic. Antioxidants included green walnut hull extract, green tea, ellagic acid from pomegranate, curcumin in turmeric, and rosemary. Urea, salicylic acid, zinc lactate, and glycerin promoted hydration and keratolysis. Lesions were covered with 3M Nexcare® dressings. Softened SK debris was removed with an emery board. The appearance of the SKs was improved in five cases. A 5-to-17-day course of a topical mixture composed of antioxidant, keratolytic, and hydrating agents, followed by scooping of softened SK, improved the appearance of 5 SKs. The topical antioxidant mixture reported in this pilot study warrants further investigation. J Drugs Dermatol. 2025;24(2):183-187. doi:10.36849/JDD.7977.

Extraction and Characterization of Antioxidants and Cellulose from Green Walnut Husks

The ultrasound-assisted extraction process with microwave pretreatment was modeled and optimized to maximize the yield of antioxidants from green walnut husks using a response surface methodology with Box–Behnken design. In this design, the ultrasound-assisted extraction time (10–40 min), ultrasound-assisted extraction temperature (40–60 °C), and microwave pretreatment time (20–60 s) were selected as the factors, while the total antioxidant content was defined as the response. The solvent of choice for extracting antioxidants was 50% (v/v) ethanol. After optimization using the desirability function, an ultrasound-assisted extraction time of 23 min, ultrasound-assisted extraction temperature of 60 °C, and microwave pretreatment time of 60 s were proposed as the optimal conditions and their validity was verified. Under these conditions, the experimentally determined total antioxidant content was 3.69 g of gallic acid equivalent per 100 g of dry matter. In addition to phenolics, UHPLC–ESI–MS/MS analysis indicated the presence of lipids, quinones, terpenoids, and organic acids in the extract. After the antioxidant extraction, the solid residue was further processed to isolate cellulose in line with the concept of sustainable manufacturing. The structural characterization and hydration properties of cellulose were analyzed to identify its key features and assess its potential for value-added applications. The results demonstrate that green walnut husks are a valuable and cost-effective agro-industrial byproduct for extracting antioxidants and isolating cellulose. This aligns with the principles of a circular economy and the sustainable production of natural compounds.

Genome-Wide Identification of the WD40 Gene Family in Walnut (Juglans regia L.) and Its Expression Profile in Different Colored Varieties

Abstract: The walnut (Juglans regia) is a woody oilseed crop with high economic and food value as its kernels are edible and its hulls can be widely used in oil extraction and plugging, chemical raw materials, and water purification. Currently, red walnut varieties have emerged, attracting consumer interest due to their high nutritional values as they are rich in anthocyanins. WD40 is a widespread superfamily in eukaryotes that play roles in plant color regulation and resistance to stresses. In order to screen for JrWD40 associated with walnut color, we identified 265 JrWD40s in walnuts by genome-wide identification, which were unevenly distributed on 16 chromosomes. According to the phylogenetic tree, all JrWD40s were classified into six clades. WGD (Whole genome duplication) is the main reason for the expansion of the JrWD40 gene family. JrWD40s were relatively conserved during evolution, but their gene structures were highly varied; lower sequence similarity may be the main reason for the functional diversity of JrWD40s. Some JrWD40s were highly expressed only in red or green walnuts. In addition, we screened 16 unique JrWD40s to walnuts based on collinearity analysis. By qRT-PCR, we found that JrWD40-133, JrWD40-150, JrWD40-155, and JrWD40-206 may regulate anthocyanin synthesis through positive regulation, whereas JrWD40-65, JrWD40-172, JrWD40-191, JrWD40-224, and JrWD40-254 may inhibit anthocyanin synthesis, suggesting that these JrWD40s are key genes affecting walnut color variation.

Characterizing Dyeing Constituents from Walnut Green Husks: Utilization of a Harmful Agricultural By-product as Natural Dye to Alleviate Its Environmental Pollution

Walnut green husks (WGHs), a by-product of walnut cultivation, poses significant environmental concerns due to their indiscriminate disposal practices. To alleviate this problem, this study explored the possibility of utilizing WGHs as a resource of natural dyes focusing on the characterization of responsible bioactive compounds. The crude aqueous extract of WGHs displayed excellent dyeing activity on fabrics, resulting in a brownish color; further chromatographic fractionation revealed that the distilled water (dH2O) fraction of the extract yielded from macroporous resin column chromatography exhibited the best dyeing effect compared with other ethanol-based fractions (20%, 60%, and 90%). Based on the subsequent LC-MS/MS, FTIR, and UV-Vis analysis, six most dominant, colored compounds that are commercially available were chosen for evaluating their dyeing capacity, including β-carotene, 2,4-dinitrophenol, phylloquinone, astaxanthin, quercetin 3-sambubioside and avicularin, and indeed their mixture displayed similar dyeing effect as the dH2O fraction and the crude extract of WGHs on fabrics. The isolated compounds and their mixture exhibited comparable dyeing performance to the crude extract, with notable K/S color strength values. Colorimetric analysis revealed distinct CIEL*a*b* values for each compound; furthermore, the dyed fabrics demonstrated moderate-excellent colorfastness. Our study implied that WGHs extract and ingredients have the potential to be utilized as natural dyeing agents, which provides a new insight for eliminating environmental pollution triggered by hazardous agricultural wastes.

FLAVONOID AND TOTAL PHENOLIC CONTENTS OF GREEN WALNUT FRUITS AND LEAVES, AND THE EFFECTS OF THEIR EXTRACTS ON THE MICROBIOLOGICAL PROPERTIES OF KURUT

Kurut is a traditional dairy product, rich in protein and minerals, made by salting and drying strained yoghurt. This study investigates the effect of green walnut and green walnut leaf extracts on the microbiological properties of kurut samples. Kurut samples were prepared in seven groups using traditional methods. Seven groups of 300 g kurut samples were prepared using traditional methods. Groups GWL5, GWL10, and GWL15 were supplemented with 5 mg, 10 mg, and 15 mg of walnut leaf extract, while groups GWF5, GWF10, and GWF15 received 5 mg, 10 mg, and 15 mg of green walnut fruit extract. The seventh group was designated as the control group. Results indicated that the GWL15 group significantly inhibited the growth of Enterobacteriaceae spp. and Staphylococcus-Micrococcus bacteria. This suggests that incorporating walnut leaves into kurut production could inhibit bacterial growth, potentially extending shelf life and providing health benefits due to its bioactive components.

Phytochemical Constituents from the Green Walnut Husk of Juglans mandshurica

Phytochemical Constituents from the Green Walnut Husk of Juglans mandshurica

Beneficial clinical effects of honey from bees fed with specific plant extracts

Abstract Background Our team has demonstrated in a number of pre-clinical studies that special bees fed with syrups containing natural plant extracts contain a number of active substances that have beneficial effects on the human body. We have previously reported that bees fed with green walnut have beneficial effects on sugar metabolism, lowering serum glucose levels and reducing insulin resistance. Methods We conducted a prospective double-blind functional food study with 45 healthy volunteers using a strict inclusion and exclusion criteria with ethical approval. Participants ate 30 gramms of honey layered under 150 ml of yoghurt twice a day for 3 weeks. Fifteen participants consumed honey from bees fed with green walnut extract, while 15 participants consumed honey from bees fed with sea buckthorn extract, and 15 participants in the control group consumed acacia honey. Sleep quality was assessed with the SQS questionnaire, and quality of life with the SF-36, EORTC Q-C30 and EQ-5D tests on days 0 and 22 of the study. Results Consumption of both specific honey resulted improvements in the life quality parameters and in the sleep quality. ‘Buckthorn honey’ showed significant differences after the 3rd week: physical function improved (25.3±0.5 vs 27.4±2.8; p = 0.04), anxiety-depression decreased (1.4±3.6 vs 1±0.3; p = 0.03), complex physical status (84.1±9.7 vs 88.7±6.9; p = 0. 04), while ‘green walnut honey’ improved EQ-5D complex quality of life (84.1±9.7 vs 88.9±6.9; p = 0.01), overall quality of life functioning (90.6±14.9 vs 99.2±4.2; p = 0.03), EORTC Q-C30 total score (467.1±30.6 vs 487.4±21.4; p = 0.03).No such positive effects were confirmed in the control group. Conclusions Honey from bees fed with sea buckthorn extract has many beneficial physiological effects on the human body, improving physical well-being and reducing anxiety and depression. Honey from bees fed with green walnut extract improves the complex quality of life. Key messages • Improving the quality of life with nutrition is an increasingly important research field, playing a key role in our life. • Our research has shown that honey from bees fed with green walnut and sea buckthorn extract improves several parameters in the quality of life.

Evaluation and prediction of synergistic antioxidant effects of green walnut hulls, potato peel, and date pulp extracts on the stability of sunflower oil by deep neural networks

Evaluation and prediction of synergistic antioxidant effects of green walnut hulls, potato peel, and date pulp extracts on the stability of sunflower oil by deep neural networks

Basics of modern modeling and expansion of the relativity theory of time in the field of classical physics

Throughout history, many scientists considered time as the result of changing the world and believed that time is not true. Among those who say that time is not true, Einstein is the only one who was able to mathematically explain the relativity of time in the field of geometry (space time) and present his equations in relativistic physics. Although Einstein, like other scientists, did not provide a clear definition of time, he presented the relativity of time well. He showed that time is not independent of space and bends along with space. Also, Einstein used the speed of light to convert mass into energy to introduce the law of mass–energy equivalence. Currently, basic laws such as conservation of mass, conservation of energy and equivalence of mass and energy have been presented. Recently, due to the importance of time in the development of science, especially in the field of water and chemistry, “timemass equivalence law” has also been presented (by the author). In this research, with the aim of expanding the relativity of time in the flows of mass and energy (not the field of motion and geometry), while presenting new definitions of “phenomenon”, “time” and “specific speed of transformation”, in addition to the theory of “mass equivalence law” “Time” was completed, the general equations of equivalence of energy time—and timemass were introduced. Then, to check the results more accurately, the general masstime equation (in this study, absorption kinetics) by performing surface absorption experiments of heavy metals (Fe + 2, Pb + 2, Zn + 2, Ni + 2, Cd + 2, Cu + 2)) was investigated by the adsorbents of green walnut shell (GWH) and its biochar (GWHB), and the results are tested in different ways.

Determination of Quercetin in Iraqi Green Walnut Husk via Green Ionic Liquid-Based Digestion Extraction and Gel Filtration Procedures-Spectrophotometry and Microfluidic Paper-Based Analytical Platform Detection

في هذه الدراسة تم استخلاص ،عزل وتقدير الكيورستين الموجود في قشور الجوز العراقي باستخدام طريقة جديدة تعتمد على الاستخلاص بطريقة الهضم المبنية على استخدام السوائل الايونية و طريقة الترشيح بالجل للفصل المقترنة مع المطيافية الضوئية للتقدير ومن ثم مقارنتها مع تقنية جديدة تسمى تقنية السوائل المايكروية الورقية مستهدفة بناء طريقة اقتصادية، صديقة للبيئة وخضراء. ولقد تم اختيار 1 بيوتيل-3-مثيل ايمادزوليم كلورايد كمذيب اخضر بديل للمذيبات التقليدية بسبب خصائصة الذوبانية .ولقد اظهرت النتائج ان 100 ملغرام من القشورتحتاج الى 15 مل من المذيب و30 دقيقة من الهضم عند درجة75°C كظروف مثلى لاعطاء افضل ناتج للمستخلص بطريقة الهضم مقارنه مع طرق الاستخلاص الاخرى .تحت هذه الظروف المثلى تم عزل الكيورستين باستخدام طريقة الترشيح بالجل وتم التاكد من المركب المعزول باستخدام تقنية كروموتوغرافيا السائل عالية الاداء و اشعة فورية تحت الحمراء .تم تقدير الكيورستين المعزول من المستخلص لونيا ( طريقة كلوريد الالمنيوم) باستخدام طريقتي المطيافية الضوئية و وتقنية السوائل المايكروية الورقية معطيا الخطية لمنحنيات المعايرة لكلتا الطريقيتين بين 10-100 مليغرام / لتر مع معامل ارتباط0.9369 و 0.7917 لكلتا الطريقتين. ومن ثم تم تقدير الفعالية المضادة للاكسدة باستخجام طريقة قوة الاختزال للمركب المعزول مظهرة فعالية مضادة للاكسدة جيدة و بين تحليل التباين (ANOVA) عدم وجود فرق كبير بين تقنية المطيافية الضوئية وتقنية السوائل المايكروية الورقية. كخلاصة يمكن اعتبار المذيب الايوني BMIMCLمذيبا امنا ومناسبا لاستخلاص المركبات النباتية ذات الخواص الطبية وكذلك فان تقنية السوائل المايكروية الورقية اثبتت مقدرتها على التحليل بكفاءة مساوية الى طرق التحليل التقليدية بالاضافة الى خصائصها الخضراء.

Research on Detection Algorithm of Green Walnut in Complex Environment

The growth environment of green walnuts is complex. In the actual picking and identification process, interference from near-background colors, occlusion by branches and leaves, and excessive model complexity pose higher demands on the performance of walnut detection algorithms. Therefore, a lightweight walnut detection algorithm suitable for complex environments is proposed based on YOLOv5s. First, the backbone network is reconstructed using the lightweight GhostNet network, laying the foundation for a lightweight model architecture. Next, the C3 structure in the feature fusion layer is optimized by proposing a lightweight C3 structure to enhance the model’s focus on important walnut features. Finally, the loss function is improved to address the problems of target loss and gradient adaptability during training. To further reduce model complexity, the improved algorithm undergoes pruning and knowledge distillation operations, and is then deployed and tested on small edge devices. Experimental results show that compared to the original YOLOv5s model, the improved algorithm reduces the number of parameters by 72.9% and the amount of computation by 84.1%. The mAP0.5 increased by 1.1%, the precision increased by 0.7%, the recall increased by 0.3%, and the FPS is 179.6% of the original model, meeting the real-time detection needs for walnut recognition and providing a reference for walnut harvesting identification.

Preparation of multi-barrier and multi-functional paper-based materials by chitosan, ethyl cellulose and green walnut husk biorefinery products for sustainable food packaging

The growing interest in paper-based materials for packaging is driven by their renewable and eco-friendly characteristics. However, their poor barrier performance against water, oil, and gas limits their application in the food packaging industry. In this study, we developed a simple dual-layer coating method to create water- and oil-repellent, gas barrier, antioxidant, and antibacterial paper-based materials using naturally-derived materials, including chitosan (CS), ethyl cellulose (EC), and cascade biorefinery products from green walnut husk (GWHE and CNC). The bottom CS/CNC oil-resistant coating and the top EC/GWHE water-resistant coating were applied to the paper surface. The synergistic effect of these coatings enhances the gas barrier and imparts functional properties to the paper. Compared to uncoated paper, the dual-layer-coated paper demonstrated a 239.1 % increase in tensile index, a higher kit rating value of 12/12, a lower Cobb 60 value of 3.21 mg/m2, a 44.0 % decrease in water vapor permeability (WVP), and a 90.7 % reduction in air permeability (AP). Additionally, this coated paper exhibited good antioxidant and antibacterial properties and favorable biodegradability. This study provides novel insights into the valorization of GWH waste and presents a sustainable strategy for producing high-performance paper-based materials for food packaging applications.

Bactericidal activity of preparations based on Juglans Regia against certified bacterial test cultures

Objective. To study the bactericidal activity of a number ofpreparations obtained by different technological processes from plant materials of individual parts of the Green walnuts on several certified model strains of bacteria that differ in biological diversity. To determine the disinfectant capabilities of these preparations in the absence of antagonistic and synergistic effects of the full range of mixtures of typical banal microflora of pig farms. Methods. The following methods were used: biological and botanical to determine the phase of vegetation of Juglans regia in the selection of raw materials from different parts of the plant; biochemical and chemical in the process of preparation and isolation of the active substance from these samples and their purification from ballast fiber by maceration and extraction, using a number of devices and equipment; microbiological for the preparation of standardized culture media with selective properties that correspond to the peculiarities of reproduction, development and distribution of selected model strains. Surface inoculation was performed on liquid and agar-based culture media in test tubes and Petri dishes using the standard streak plate method with a microbiological loop. Subsequently, standard incubation at 37°C for 24 hours was performed. Results. It was found that the greatest bactericidal and fungicidal activity, and therefore potential effectiveness as a possible disinfectant in organic pig production technology, was found in extracts of phytomaterials of Juglans regia L - potential disinfectants No. 2 (extractant - 5 % acetic acid, wax-ripening nut) and No. 4 (extractant - 20 % alcohol, wax ripening nut) - brought to 5 % alcohol after obtaining the primary extract. Conclusions. According to the results of studies on certified strains of microorganisms, it was found that the studied extracts have a significant effect on representatives of enterobacteria, a weak effect on spore forming bacilli. Keywords: organic pig production, bactericidal activity, phytodesinfectant, certified test cultures, Salmonella typhimurium, Bacillus subtilis, extract, walnut.

Preparation of Eco-Friendly Composite Material for Mercury (II) Adsorption Including Non-Wood Content From Walnut Green Husk (Juglon Regia L.): Experimental and Theoretical Studies

In this study, the adsorption properties of a composite material consisting of polyacrylamide, an inert polymer, and an extract obtained from the water-soluble part of a green walnut shell were investigated for Hg(II) ions. SEM, EDX, FTIR, and PZC analyses were performed to characterize the newly synthesized material. SEM and EDX analyses confirmed that the surface of the synthesized adsorbent became softer and smoother after adsorption, indicating the presence of Hg in its elemental composition. FTIR analysis showed that mercury enters the structure through chemical interactions, and there are changes in bond vibration frequencies in the presence of Hg(II). According to the PZC point analysis, the point at which the surface charge was zero was found to be pH 4. The Langmuir model was used to calculate the adsorption capacity after investigating the effect of concentration on adsorption. The adsorption capacity was found to be 1.808 molkg−1 (362,67 mgg−1) from the Langmuir model, which is very high compared to similar adsorbents. PFO model was used to explain the adsorption kinetics and very fast adsorption kinetics were observed. The adsorption entropy increased, free enthalpy of adsorption was negative, and heat of adsorption was in the energy-consuming direction.

Valorization of various nut residues grown in Turkiye: Antioxidant, anticholinesterase, antidiabetic, and cytotoxic activities.

The utilization of plant-based residues has been extensively employed for the control of diverse illnesses, owing to their safety and minimal adverse effects. In the current study, it was aimed for the characterization of the bioactive, enzyme inhibitory, and cytotoxic activities of fresh pistachio shell skin (FPSS), green walnut husk and walnut membrane (GWH), almond outer shell and inner brown skin (ASIS), as well as peanut husk and inner skin (PHIS) to be used as industrial food processing by-products. The results showed that the samples exhibited different extraction yields, with GWH having the highest percentage at 15.18%, followed by FPSS at 12.81%, ASIS at 10.29%, and PHIS at 7.80%. FPSS had the highest total phenolic content (16.28 mg gallic acid equivalents (GAE)/g) as well as the best antioxidant capabilities for DPPH (8.96 mg Trolox equivalent (TE)/g), FRAP (11.46 mg TE/g), and ABTS (22.38 mg TE/g) assays. FPSS was followed by PHIS, ASIS, and GWH, respectively. Moreover, the extracts exhibited relatively low activity against acetylcholinesterase, α-glucosidase, and α-amylase compared to standard acarbose or galantamine. Furthermore, the extracts may have the potential to induce cytotoxic effects, varying from moderate to mild, on both cancerous (IC50 = 454.55-617.28 μg/mL) and healthy cells (IC50 = 438.60-490.20 μg/mL). The results of this research showed that shell residues of nut hold promise for a variety of industrial applications spanning the food, pharmaceutical, and cosmetic sectors.

Adsorption of the Antibiotic Roxithromycin on Low-Cost Food Waste Materials: Batch and Column Studies

Antibiotics are widely utilized for a variety of medical conditions. Antibiotic residues in wastewater are dangerous to all living beings. Antibiotics remain in the wastewater environment when general treatment plant technologies are employed. The literature has numerous techniques for getting rid of antibiotics. Compared to other techniques for removing contaminants in the solution environment, the adsorption method is preferred due to its benefits, such as ease of use, high efficiency, and low cost. The study investigated using the green walnut shell (GWS), a natural sorbent, as an adsorbent to discharge roxithromycin (ROX) antibiotics from the solution medium. Adsorption conditions were studied in batch and continuous systems. pH, adsorbent amount, interaction time, sorbate concentration, and salt effect parameters were investigated in the batch system. The data obtained were calculated with kinetic and isotherm models. The adsorption process has been based on the so-called pseudo-second-order kinetic model. GWS was characterized using SEM and FTIR techniques. The amount of absorbent, flow rate, and breakdown in the continuous system were explored. In the batch system, the adsorption equilibrium was set up at the solution's original pH with 0.1 g of adsorbent in 40 minutes, and 79% ROX removal was achieved. The optimum flow rate and adsorbent amount in the continuous system were determined as 0.1 mL/min and 0.3 g, respectively.

Global Perspectives on the Medicinal Implications of Green Walnut and Its Benefits: A Comprehensive Review

Green walnuts have been valued for their health and medicinal effects for many years. Green walnuts have several bioactive metabolites, including polyphenols, flavonoids, and tannins, that have antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. With previous records of increased inclination towards natural or botanical sources of therapeutics, green walnuts have regained the uniqueness of therapeutic prominence globally. This comprehensive review provides a deep understanding of the use of green walnut (Juglans regia L.) around the globe and shows its potential pharmacological benefits. It explores the different therapeutic and medicinal uses of green walnuts, including their historical use in traditional medicine throughout different continents and regions, including Asia, Europe, America, Africa, and the Middle East. This review also provides the substantial studies conducted on green walnuts, which investigate the bioactive substances found in various parts of the walnut tree, including the kernel, shell, leaves, shoots, bark, and roots, indulging in their health advantages. It also diversifies the antibacterial, antioxidant, anti-inflammatory, cardiovascular, and antihypertensive activities of the green walnut, which clearly shows the prospective use of the walnut in nutraceutical and medicinal applications. This review continues by emphasizing the necessity for further research to focus on and attract global researchers to aim for a detailed understanding of the pharmacological implications of green walnuts and enhance their use in traditional and modern medicine.

Impact of Various Drying Technologies on the Drying Characteristics, Physico-chemical Properties, and Antioxidant Capacity of Walnut Green Husk

Impact of Various Drying Technologies on the Drying Characteristics, Physico-chemical Properties, and Antioxidant Capacity of Walnut Green Husk

A new study on the corrosion inhibition mechanism of green walnut husk extract as an agricultural waste for steel protection in HCl solution

In this study, green walnut husk (GWH) extract was explored as a cost-effective (waste-agricultural) and eco-friendly inhibitor to increase the corrosion resistance of carbon steel in a 1 M HCl solution. Electrochemical impedance spectroscopy, weight change, and potentiodynamic polarization (PDP) tests were utilized to examine the electrochemical behavior of steel substrates with and without the inhibitor. Atomic force microscopy (AFM), field emission scanning microscopy, Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) were performed to analyze corroded surface structures with and without the inhibitor. This inhibitor was found to be 27–82 % efficient in increasing the corrosion resistance of the steel substrates. When the temperature of the solution was increased from 303 to 323 K, the retardation coefficient decreased due to the physical adsorption of GWH molecules on the surface. The results indicated that GWH acted as a mixed inhibitor, and its adsorption on the surface followed the Langmuir model. AFM measurements showed that the roughness of corroded surfaces decreased by approximately 22 % when the GWH concentration was at its optimum level of 400 ppm. Thermodynamic studies displayed a decrease in the corrosion reaction's activation energy of about 25 %. FTIR and XRD patterns of corroded surfaces represented that hydrated iron chloride was the dominant corrosion product. Furthermore, the results provided insight into the GWH adsorption mechanism.

Exploring the Ecological Implications, Gastronomic Applications, and Nutritional and Therapeutic Potential of Juglans regia L. (Green Walnut): A Comprehensive Review.

The green walnut, which is frequently overlooked in favor of its more mature sibling, is becoming a topic of great significance because of its unique ecological role, culinary flexibility, and therapeutic richness. The investigation of the bioactive substances found in green walnuts and their possible effects on human health has therapeutic potential. Juglans regia L. is an important ecological component that affects soil health, biodiversity, and the overall ecological dynamic in habitats. Comprehending and recording these consequences are essential for environmental management and sustainable land-use strategies. Regarding cuisine, while black walnuts are frequently the main attraction, green walnuts have distinct tastes and textures that are used in a variety of dishes. Culinary innovation and the preservation of cultural food heritage depend on the understanding and exploration of these gastronomic characteristics. Omega-3 fatty acids, antioxidants, vitamins, and minerals are abundant in green walnuts, which have a comprehensive nutritional profile. Walnuts possess a wide range of pharmacological properties, including antioxidant, antibacterial, antiviral, anticancer, anti-inflammatory, and cognitive-function-enhancing properties. Consuming green walnuts as part of one's diet helps with antioxidant defense, cardiovascular health, and general well-being. Juglans regia L., with its distinctive flavor and texture combination, is not only a delicious food but also supports sustainable nutrition practices. This review explores the nutritional and pharmacological properties of green walnuts, which can be further used for studies in various food and pharmaceutical applications.