Great Neck Research Articles

Response to the Letter to the Editor From Jeffrey Brent, MD, PhD. Re: Mesothelioma Associated With the Use of Cosmetic Talc.

Department of Occupational Medicine, Epidemiology and Prevention, Northwell Health, Great Neck, NY Conflicts of interest: The author has served as an expert witness in asbestos litigation on behalf of plaintiffs, including in cases in which patients with cosmetic talc exposure developed mesothelioma. Address correspondence to: Jacqueline Moline, MD, MSc, FACP, FACOEM, Department of Occupational Medicine, Epidemiology and Prevention, Northwell Health, 175 Community Dr, Suite 206, Great Neck, NY 11021 ([email protected]).

PD11-04 EFFECT OF HEALTH AND AGE ON TOTAL TESTOSTERONE: HEALTHY MEN HAVE HIGHER TESTOSTERONE REGARDLESS OF AGE

You have accessJournal of UrologyCME1 Apr 2023PD11-04 EFFECT OF HEALTH AND AGE ON TOTAL TESTOSTERONE: HEALTHY MEN HAVE HIGHER TESTOSTERONE REGARDLESS OF AGE William Shyr, Jonathan Davilla, Darius Paduch, and Great Neck William ShyrWilliam Shyr More articles by this author , Jonathan DavillaJonathan Davilla More articles by this author , Darius PaduchDarius Paduch More articles by this author , and Great NeckGreat Neck More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003251.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The arbitrary cut-off total testosterone (TT) level of 300 ng/dL is used to diagnose hypogonadism in men of all ages, although intuitively, younger men should have higher TT levels. There is growing evidence that TT level is a proxy of men’s overall health. This study aimed to analyze the effects of age, common comorbidities, and body mass index (BMI) on TT. METHODS: Data from the 2013-2016 NHANES survey were analyzed. TT was measured using liquid chromatography-mass spectrometry certified by the CDC. Only men 18-79 years old were evaluated in the study. Men taking testosterone and aromatase inhibitors were excluded. We conducted a multivariate analysis of the following risk factors for low TT: age, BMI, diabetes mellitus (DM), hypertension (HTN), hypercholesterolemia, and coronary artery disease (CAD). DM was defined as HgA1c ≥ 6.5% or diagnosis by a physician, and hypercholesterolemia as cholesterol above 240 mg/dL or diagnosis by a physician. Healthy men were defined as men with BMI <24.9 without any of the above risk factors. Linear and local polynomial regression models were used for fitting TT. The t-test was used to compare mean TT between groups. Statistical significance (SS) was set at p<0.05. RESULTS: The study consisted of 4,615 men with a median age of 46 years. Multivariate analysis showed that hypercholesterolemia (p<0.001), DM (p=0.03), and elevated BMI (p<0.001) were predictors of low TT. Neither age nor HTN was SS for TT in the multivariate analysis. With age, TT level slightly decreased, especially from 18 to 34. There were twice as many hypogonadal (TT < 300 ng/dL) men at the age of 34 than at the age of 18 (25% v 12.5%; p<0.001). The overall mean TT level for healthy men was higher at 522 ng/dL (95%CI: 506-538) than unhealthy men at 390 ng/dL (95%CI: 382-398) (p<0.001) (Figure 1). Mean values of TT in both healthy men and men with comorbidities are higher than the cutoff value of 300 ng/dL. CONCLUSIONS: Obesity, even being overweight, and poor cardiovascular health, but not age, are strongly associated with lower TT. Healthy men, regardless of age, typically have TT levels above 500 ng/dL. Our study suggests that weight loss, controlling DM and cardiovascular risk factors likely increase TT, and such interventions should be discussed with patients in addition to testosterone therapy. Source of Funding: Fracchia Research Scholarship © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e333 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information William Shyr More articles by this author Jonathan Davilla More articles by this author Darius Paduch More articles by this author Great Neck More articles by this author Expand All Advertisement PDF downloadLoading ...

Editorial Commentary.

No AccessUrology Practicethe Specialty1 Mar 2023Editorial CommentaryThis article comments on the following:Advanced Urology Boot Camp: A Simulation-based Curriculum to Enhance Fourth-year Medical Student Procedural Competency Alexandra L. Tabakin and Sammy E. Elsamra Alexandra L. TabakinAlexandra L. Tabakin * E-mail Address: [email protected] Division of Female Pelvic Medicine and Reconstructive Surgery, Donald and Barbara Zucker School of Medicine and Hofstra/Northwell, Great Neck, New York More articles by this author and Sammy E. ElsamraSammy E. Elsamra Division of Urology, Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey More articles by this author View All Author Informationhttps://doi.org/10.1097/UPJ.0000000000000379.01AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Editorial Commentary." Urology Practice, 10(2), p. 201

How I Manage Hypertension and Proteinuria Associated with VEGF Inhibitor.

1Division of Nephrology & Hypertension, University Hospitals Cleveland Medical Center, Cleveland, Ohio 2Division of Kidney Diseases and Hypertension, The Glomerular Center at Northwell, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, New York 3Department of Nephrology, Peupliers Private Hospital, Ramsay Générale de Santé, Paris, France Correspondence: Dr. Arash Rashidi, Division of Nephrology & Hypertension, University Hospitals Cleveland Medical Center, 11100 Euclid Ave., Cleveland, OH 44106. Email: [email protected] Published online ahead of print. Publication date available at www.cjasn.org.

Contributors

Contributors

“If That Be Treason, Let Them Make the Most of It!”: Olin Downes, the Spanish Civil War, and Civil Liberties in the United States

“If That Be Treason, Let Them Make the Most of It!”: Olin Downes, the Spanish Civil War, and Civil Liberties in the United States

Находки серебряных шейных гривен «с фасетированным обручем и замком в двойную петлю» эпохи Великого переселения народов с территории Белорусского Понеманья и Подвинья

The article addresses a series of finds of silver neck rings from the Migration Period — two whole (Afieraŭščyna, Vialikaje Sialo) and one fragmented (Haradzišča) specimen — from the territory of Belarusian Neman and Dvina Regions, belonging to the type that in Russian-language literature is called neck rings “with a faceted hoop and a double-loop lock”. The dating of finds from Afieraŭščyna and Vialikaje Sialo can be determined on the basis of analogies within the framework of the 5th and, possibly, 6th centuries. The situation with a fragment of a neck ring from the open settlement Haradzišča is more complicated. Considering the fact that this artifact was found in fragmented form, in fact — as a weight silver, one cannot exclude that it could fall into obsolescence somewhat later than other neck rings of this type, and can be dated within the 5th—7th centuries. The finds of silver neck rings “with a faceted hoop and a double-loop lock” from the territory of Belarusian Neman and Dvina Regions significantly broaden the knowledge of the area of distribution of this type of the Great Migration Period neck rings.

The Adjustable Intragastric Balloon for Treatment of Obesity: Results of a Multicenter, Randomized Controlled Trial

Background: Intragastric balloons are anatomy preserving, minimally invasive therapies for obesity. Enhanced tolerance and durability inform clinical adoption. We investigated the safety and efficacy of an adjustable intragastric balloon (aIGB) with prolonged dwelling time in adults with obesity.Methods: Patients were randomized to the Spatz3 (Spatz FGIA, Great Neck, NY) aIGB with lifestyle intervention versus lifestyle intervention alone (control) for 32 weeks. The aIGB volume could be increased to facilitate weight loss or decreased for tolerability. Co-primary endpoints included mean total body weight loss (TBL) and responder rate (≥ 5% TBL) at 32 weeks. Weight loss maintenance (WLM) was reported at 14 months. Improvement in obesity-related comorbidities was reported at 32 weeks. Data were analyzed in a multiple imputed intention to treat (miITT) population. Adverse events were recorded throughout the study duration.Findings: 288 adults with obesity were randomized to aIGB (n = 187) or control (n = 101) arms. Mean TBL was 15‧0% [95% CI 13‧9%, 16‧1%] in the aIGB group vs 3‧3% [95% CI 2‧0%,4‧6%] in controls (p Interpretation: The adjustable intragastric balloon induced significant weight loss that was maintained in most patients. Adjustability of volume significantly improved safety and tolerance highlighting advantages of this therapy for clinical practice.Trial Registration: This study was registered with clinicaltrial.gov -NCT02812160.Funding: SPATZ MedicalDeclaration of Interest: BKA reports consultant roles with Endogenex, Endo-TAGSS, Metamodix, and BFKW; consultant and grant/research support from USGI, Cairn Diagnostics, Aspire Bariatrics, Boston Scientific; Speaker roles with Olympus, Johnson and Johnson; speaker and grant/research support from Medtronic, Endogastric solutions; and research support from Apollo Endosurgery, and Spatz Medical. CGC reports consultant roles with Olympus; consultant roles and payment or honoraria Apollo Endosurgery, Boston Scientific; payment or honoraria from Abbive; participation in a Data Safety Monitoring Board and consultant roles with ERBE, BFKW Inc, and Nitinotes Surgical. VP reports consultancy fees from Obalon Therapeutics Inc. PJ reports grants from Boston Scientific; licenses to Endosim; consulting fees from Endogastric solutions, ERBE; support for meetings from USGI medical; consulting fees and research support from GI dynamics; research support from Apollo Endosurgery, and Fractyl. AA reports grants from NIH-NIDDK, American Neurogastroenterology and Motility Society, Mayo Clinic Center for Individualized Medicine; Stockholder of Gila Therapeutics, and Phenomix Sciences; personal fees from Rhythm Pharmaceuticals, General Mills, Gila Therapeutics; he reports patent PCT. US 62/589,915 licensed to Phenomix Sciences. ACS reports institutional research grants from Boston Scientific, Enterasense, Endogenex; consulting fees from Olympus; consulting fees and research grants from Endo-TAGSS, and Apollo Endosurgery; Participation in Data Safety Monitoring Board with GI Dynamics, and ERBE. MR reports consultant roles with Boston Scientific, Fujifilm, Medtronic, Enterasense, and GI Windows; Consultant and research support from Cook Medical. DM reports financial support from SPATZ medical for statistical analysis for this trial. CCT reports institutional research grants from Aspire Bariatrics, ERBE, SPATZ; Royalties from Endosim, Enterasense; Consulting fees and research grants from Apollo Endosurgery, Boston Scientific, Covidien/ Medtronic, Fractyl, Fujifilm, GI Dynamics, Lumendi, Olympus, and USGI; Payment or honoraria from Boston Scientific and Olympus; Patents licensed to Boston Scientific, GI Windows, Enterasense, EnVision Endoscopy, Endosim; Participation in Data Safety Monitoring Board with GI Dynamics, Fractyl, USGI; Leadership or fiduciary role in other board with Enterasense, EnVision Endoscopy, GI Windows, ASGE Governing board, BlueFlame Healthcare Venture Fund; Stockholder in GI Windows, Enterasense, EnVision Endoscopy; has received equipment on loan from Fujifilm, Olympus, and Boston Scientific. All other authors report no conflict of interests.Ethical Approval: It was conducted under a US Food and Drug Administration (FDA) Investigational Device Exemption (IDE G160061), approved on 29-Jul-2016, in compliance with 21 CFR812

Cutaneous temperature and pressure pain threshold in individuals with knee osteoarthritis.

IntroductionOsteoarthritis is a common disease in which skin temperature may be included among the pathophysiological factors. Thermography allows the mapping of cutaneous temperature and may be employed in the investigation of osteoarthritis.ObjectivesTo evaluate cutaneous temperature of the lower limbs, as well as to verify its association with pressure pain thresholds in individuals with knee osteoarthritis.Material and methodsThis case series study was conducted with individuals of both genders aged 48–77 years with unilateral knee osteoarthritis. Volunteers underwent thermographic evaluation by an infrared sensor (FLIR T650SC). The anterior region of the thigh and leg and the knee area were evaluated. Pressure pain thresholds (PPT) were evaluated by algometry (Pain Diagnostics, Great Neck, USA) at the vastus medialis, vastus lateralis, rectus femoris, and patellar tendon. Data analysis was conducted with the statistical package SPSS v.24 for Windows. Comparisons between affected and unaffected sides were made by paired Student’s t-test or the Mann-Whitney U test, and associations between variables were assessed by Pearson or Spearman’s correlation coefficient. In all cases, the significance level was set at p ≤ 0.05.ResultsEleven volunteers (63.1 ±9.5 years) participated in this study. When comparing cutaneous temperature, only the region of the knee showed a significant difference between sides (p = 0.02). There were no differences between affected and unaffected knees regarding pain tolerance (PPT) at all sites evaluated. There were also no significant associations between the study variables.ConclusionsIndividuals with knee osteoarthritis presented a higher temperature of the affected knee, but this was not associated with pressure pain thresholds.

Waste to Energy Realized at Long Island Wastewater Treatment Facility

New York's Great Neck Water Pollution Control District operates a 5‐mgd wastewater treatment facility that is turning waste products into electricity and heat as well as saving money for the utility district and ratepayers.

Dream Machines: The Motorcar as Sign of Conquest and Destruction in F. Scott Fitzgerald's &lt;em&gt;The Great Gatsby&lt;/em&gt;

Dream Machines: The Motorcar as Sign of Conquest and Destruction in F. Scott Fitzgerald's &lt;em&gt;The Great Gatsby&lt;/em&gt;

Boats Against the Current: The Honeymoon Summer of Scott and Zelda: Westport, Connecticut, 1920

Boats Against the Current: The Honeymoon Summer of Scott and Zelda: Westport, Connecticut, 1920

Last Kiss The Great Gatsby The Great Gatsby: An Edition of the Manuscript

Last Kiss The Great Gatsby The Great Gatsby: An Edition of the Manuscript

No One is Coming to Save Us

No One is Coming to Save Us

Clinical Case: Treatment of a Giant Cells Tumor of the Proximal Femur in a Disadvantaged Area

There have been not many reports on the result of intralesional excision for giant cell tumors (GCTs) of the great trochanter and femoral neck because of its rarity. The authors present the case of a 35-year-old female patient managed with intralesional curettage and filling the defect with autologous bone graft from iliac crest. An appoint of three doses of Denosumab was done postoperatively. The article discusses the clinical aspects and surgical treatment, and the benefits of Denosumab. This report aimed to demonstrate the possibility to perform curetage for giant cell tumor of the hip even the recommandation for this location is wide resection and endoprothesis fixation.

Neck injuries: literature review

One of the most difficult and urgent problems of the present-day surgery is the treatment of patients with neck injuries. Massive hemorrhage, asphyxia, air embolism caused by the damage of the great neck vessels; the combined injuries of hollow organs determine the progressive destabilization of the vital functions of organism, the condition severity and high mortality of this category of patients. This article presents a review of the literature dedicated to diagnostics and treatment of neck injuries. The review highlights such issues as the history of the development of views on the neck injuries, epidemiology, classification, diagnostics and treatment.

Scope and Status of Vegetable Seed Production in Ethiopia

This paper reviewed the scope and status of vegetable seed production in order to assess the current vegetable seed supply, production, distribution scenario and production potential. Adaptation and demonstration of improved vegetable technologies have shown the potential of producing different types of vegetable in different agro climatic regions in the country. It is important to identify suitable production belts and establish model seed multiplication scheme with strong collaboration of research, farmers/growers, seed distributors, vegetable producers and the extension sector. It is important to encourage private sectors that are interested in the horticulture seed industry. In many Asian countries the seed are commercially handled in which the market share of the private sector is more than 80%. It is important that variety development program be linked with the seed system. In additions, the economics of seed production be considered to assist farmers for decision. For efficient, economic and sustainable seed supply, seed production should be decentralized into major crop production zones with active participation of both public and private sectors. At the same time, the local seed supply should be organized using both local and improved varieties through secondary seed multiplication scheme. Improved seed production and distribution are predominantly carried out in the public sector; the scope of the formal seed supply systems is limited in developing countries like Ethiopia. Though there is huge potential; horticultural crop production and multiplication of improved variety of the seed is a great bottle neck problem. Lack of varieties and inadequate breeder and basic seed supply for effective seed production, limited technical and managerial experience and material resource absence of specialized seed farms in adequate coverage of economically important crops and lack of independent quality seed control system specially the foreign seed should be addressed by the responsible seed center.

Espetáculo e performatividade em Na Captura dos Friedmans

A partir da contraposição entre vários depoimentos, a montagem de Na Captura dos Friedmans (2003) põe em dúvida os procedimentos utilizados pela justiça e pela mídia para criminalizar Arnold e Jesse Friedman, acusados de abuso sexual contra menores em Great Neck, EUA, em 1988. O documentário recebeu elogios da crítica justamente por valorizar a ambiguidade narrativa. No entanto, buscamos mostrar que a montagem fragmentada se alinha à ideia de espetáculo, procedimento estilístico que, do ponto de vista político, se contrapõe à abertura de sentidos e à heterogeneidade de vozes que o filme mobiliza. Também chamamos atenção para o caráter performático de boa parte das imagens, pois, ele permite que sentidos e sujeitos se desloquem de lugares pré-concebidos.

Myanmar’s Mental Health System Undergoes Major Modernization

Myanmar’s Mental Health System Undergoes Major Modernization

Education Dedication

You have accessThe ASHA LeaderIn the Limelight1 Feb 2015Education DedicationEleanor Silverman devotes her considerable energy to promoting and supporting higher education. Shelley D. Hutchins Shelley D. Hutchins Google Scholar More articles by this author https://doi.org/10.1044/leader.LML.20022015.22 SectionsAbout ToolsAdd to favorites ShareFacebookTwitterLinked In Name: Eleanor Silverman, MA, CCC-SLP Title: Clinical associate professor, Department of Neurology, New York University School of Medicine Contact: [email protected] Eleanor Tobis Silverman lives just blocks from Central Park—a prime location that allows her to walk to the college courses she takes at Fordham University and easily indulge in the nearby arts scene. The mother of two also does pro bono work to help foreign-born professors with effective communication and she reviews papers submitted by students at City College of New York who receive research scholarships. It’d be a busy schedule for anyone, but consider this: Silverman, a “retired” speech-language pathologist, is about to celebrate her 97th birthday. Her lengthy career includes stints as a college professor, clinical researcher, health department consultant, private practitioner and school-based SLP. Oh, and those research scholarships? They’re in her name. Having a packed schedule is nothing new to Silverman. Once her children were in school all day, this daughter of a well-educated European immigrant went back to school to complete the six hours she needed for her master’s in speech-language pathology. In addition to earning her master’s from Brooklyn College in 1953, Silverman ended up also doing all of the coursework for her doctorate, but “I never finished my thesis,” she chuckles. Her father was the reason she went into communication sciences disorders. “One morning before school, when I was about 7,” she shares, “he asked me to go upstairs and get him a tin cup. I searched and searched and couldn’t find a tin cup, so I came downstairs very frustrated, until he explained that he wanted a thin cup.” That minor miscommunication inspired her to become an SLP. Her father’s high regard for education motivated her to a 63-year career in the Great Neck, New York, school system, Hofstra University, Nassau County Department of Health, New York University and The City College of New York. Among her many career highlights, Silverman recounts years at NYU as some of her favorite. She taught in the dentistry and neurology departments for nearly two decades. In addition to her teaching, Silverman worked with her husband—a prosthodontist and and eventual chief of the prosthodontics department of the dentistry school—on developing a cleft palate clinic. She consulted for teams developing dental prostheses, advising them on shape and thickness to help patients correctly articulate. “My husband and I married speech to dentistry,” Silverman says. One of her proudest achievements came after moving into the neurology department, however. “I helped start the school’s first speech and language clinic with audiologist Alice Berkowitz,” Silverman declares. Silverman worked in NYU’s Department of Neurology until her official retirement just a few years ago. During her tenure there she focused on communication issues and recovery treatments for people with traumatic brain injuries. Silverman directed the speech and hearing clinic, conducted clinical research, taught, contributed to professional publications, gave professional and public presentations, and participated on panels—all driven by the “goal of furthering the profession of speech and language pathology.” Educating and mentoring future CSD professionals remains one of Silverman’s most ardent passions. In addition to the City College research grant in her name, she recently received an award from NYU’s Department of Neurology for another scholarship she founded. Her daughters—who both have doctorates—also benefitted from Silverman’s legacy of encouraging lifelong education. “My oldest daughter, Beth Silverman Yam, just called and is on her way to speak to a group of 40 women. She works as the clinical director of an agency [striving to end] domestic violence,” the proud mom says. “Deborah DeZure—my youngest—is an assistant provost at Michigan State University and she runs workshops on how to improve the education of professors.” Of course, Silverman brags about her grandchildren: One teaches advanced-placement English in Seattle and another is studying the Ebola virus at the National Institutes of Health. When asked about personal highlights from her long, distinguished livelihood, Silverman doesn’t discuss her publications, speeches or awards. She remembers the people. “I always found every client I worked with a challenge and all were able to show increments of improvement,” Silverman recalls, adding that “the profession is quite remarkable and I’ve recommended it to many people. It’s been a lovely career.” Author Notes Shelley D. Hutchins is content producer/editor for The ASHA Leader. [email protected] Advertising Disclaimer | Advertise With Us Advertising Disclaimer | Advertise With Us Additional Resources FiguresSourcesRelatedDetails Volume 20Issue 2February 2015 Get Permissions Add to your Mendeley library History Published in print: Feb 1, 2015 Metrics Current downloads: 157 Topicsasha-topicsleader_do_tagasha-article-typesleader-topicsCopyright & Permissions© 2015 American Speech-Language-Hearing AssociationLoading ...