Abstract The next generation of ground-based gravitational-wave interferometers is expected to generate a bounty of new astrophysical discoveries, with sensitivities and bandwidths greatly improved compared to current-generation detectors. 
These detectors will allow us to make exceptional advancements in our understanding of fundamental physics, the dynamics of dense matter, and the cosmic history of compact objects. 
The fundamental design aspects of these planned interferometers will enable these new discoveries; 
however, challenges in technical noise, data quality, and calibration have the potential to limit the scientific reach of these instruments.
In this work, we evaluate the requirements of these elements for next-generation gravitational-wave science, focusing on how these areas may impact the proposed Cosmic Explorer observatory.
We highlight multiple aspects of these fields where additional research and development is required to ensure Cosmic Explorer reaches its full potential.