The Gravitational wave burst high-energy Electromagnetic Counterpart All-sky Monitor (GECAM) is a dedicated mission for monitoring high-energy transients. Here we report the design of the GECAM Scientific Ground Segment (GSGS) in terms of the scientific requirements, including the architecture, the external interfaces, the main function, and workflow. Judging from the analysis and verification results during the commissioning phase, the GSGS functions well and is able to monitor the status of the payloads, adjust the parameters, develop the scientific observation plans, generate the scientific data products, analyze the data, etc. Thus, the on-orbit operation and scientific researches of GECAM are guaranteed.