Objectives The study aims to identify the impact of nursing students' gratitude disposition, self-reflection, and insight on their interpersonal competence. Methods This descriptive survey study was conducted among students enrolled in a nursing college. Data were collected over a two-week period starting from September 4, 2023. Students who reviewed the study information and expressed willingness to participate were included in the sample. An online survey was administered to assess the general characteristics of the nursing students, their gratitude disposition, self-reflection and insight, and interpersonal competence. Validated survey instruments were used for each variable. A total of 115 responses were analyzed using hierarchical regression analysis. Results Both gratitude disposition (β= 0.330, p<.001) and self-reflection and insight (β= 0.253, p<.002) were found to have a significant impact on interpersonal competence. The F-value of the multiple regression analysis was 23.740 (p<.001), and the R² was 0.569, indicating that the model explained approximately 56.9% of the variance in the dependent variable. This suggests that these factors are important for understanding nursing students' interpersonal competence. Potential confounding variables were controlled for to ensure the validity of the results. Conclusions This study confirms that nursing students' gratitude disposition, self-reflection, and insight significantly influence their interpersonal competence. To enhance interpersonal competence among nursing students, efforts should be made to improve their gratitude disposition and provide various opportunities for self-reflection through relevant programs. Future research should explore specific types of interventions and their effectiveness in enhancing these traits among nursing students.