Background. For many medical specialties, photography is a routine element of work. Environmental factors equally and significantly influence the interpretation of color light perception and the quality of photographic recording. Standardization of medical photography conditions is necessary for subsequent quantitative assessment of the skin scar by analyzing color coordinates in the RGB system. The goal is to determine the influence of lighting conditions and shooting distance on color coordinates when studying unaltered skin. Methods. The study involved five volunteers with no declared skin diseases and no cosmetics applied to their facial skin. Fitzpatrick skin type II - III. Digital photography was carried out using a mobile device camera at a distance of 30 cm from the subject. For each, a series of digital photographs were taken at a distance of 20, 30, 40, 50, 60, 70 cm from the light source. Color coordinates in the RGB system were measured in the digital graphics editor Adobe Photoshop CS6. Statistical analysis of the obtained data was carried out using Microsoft Office Excel 2019, Phyton 3.11. Results. Analysis of variance using the ANOVA method was used as a statistical analysis method. In order to determine the statistically significant difference between the sets, the Tukey HSD test was performed. A total of 1764 coordinates of three colors were subjected to statistical analysis (R = 588, G = 588, B = 588). When constructing a heat map of the cross-correlation of the absolute values of each color at each distance, taking into account the type of light source among themselves, the data had a strong direct correlation, regardless of the study area. When constructing a linear graph, the coordinates of any of the zones were located on the same straight line. Conclusion. Photography conditions were experimentally determined under which the color interpretation of light is constant. The results of the study should be taken into account during medical photography and subsequent color assessment of skin scars.