With the development of the Internet era, big data, artificial intelligence (AI), and other fields of innovation and change, Python has become the most popular programming tool in the digital field because of its simple grammar and convenience for students to learn. It is also one of the important skills that college computer science students need to master in the face of market demand changes. The degree of mastery of the Python language programming course directly affects students’ ability to use computers to analyze and solve problems To improve the teaching effectiveness of the “Python Language Programming” course, this paper mainly explores the integrated and blended teaching mode of said course.