Red sorghum (Sorghum bicolor (L.) Moench) stands out as a crucial dietary staple food, particularly in economically disadvantaged and food-insecure regions worldwide. Its diversity among landraces makes India a key hub for production. Red sorghum, renowned for its nutrient density and stress tolerance, holds immense potential as an alternate crop amidst climate change challenges. This review explores red sorghum's grain structure and nutritional profile, emphasizing its macronutrient and micronutrient composition, dietary fibre content, soluble sugars and bioactive secondary metabolites, including phenols, tannins and flavonoids. Understanding these aspects underscores the importance of red sorghum in addressing nutritional deficiencies and forecasting agricultural sustainability. Red sorghum offers many health benefits, particularly as a gluten-free alternative for individuals with celiac disease. Its rich phenolic compounds exhibit potential in combating carcinoma, while its starch composition, including slowly digestible starch, benefits diabetics with its low glycemic index. Combining sorghum with probiotic milk reduces oxidative stress in chronic renal disorders. Sorghum emerges as a versatile gluten-free ingredient rich in minerals and phenolic compounds, offering health benefits in various food products like cookies, RTE cereals, pasta and pet food. Additionally, exploring sorghum's genetic variations and health impacts paves the way for developing nutritionally superior varieties with robust agronomic traits.
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