Good Production Research Articles

Perancangan Dan Pembuatan Desain UI/UX Aplikasi Simpora Dengan Figma

Tanjung Pandan Customs Office as a state institution has the opportunity to compete with other customs offices in Indonesia, as an added value for the assessment of the Tanjung Pandan Customs office in its assessment in the Customs Institution. SIMPORA as an information system for Budget Absorption and Realization is made to meet these needs. The design of the application design in this study was built with Figma Application. by making a Software Design Design (DPPL), then followed by the results of the application interface is expected to make this application user friendly. This process is carried out so that with a good time frame and planning it can produce a good product as well. The results of the software interface are also equipped with design and application documentation which in the end goal is to give the Tanjung Pandan Customs office a winner in the competition between customs offices throughout Indonesia.

Enantioconvergent Hydroboration of E/Z-Mixed Trisubstituted Alkenes.

The lack of mode for chirality recognition makes it particularly challenging to carry out asymmetric transformations on E/Z-mixed minimally functionalized trisubstituted alkenes. Here, we report a catalytic enantioconvergent hydroboration of minimally functionalized trisubstituted E/Z-mixed alkenes to construct chiral organoboronic esters with excellent enantioselectivity using chiral radical cobalt catalyst. This C(sp3)-H borylation protocol showed good functional group tolerance and products could be converted to valuable compounds via C-B derivatizations. The mechanistic studies, which included control experiments, nonlinear effect experiments, deuterated labeling experiments, and X-ray diffraction, demonstrated that the favorable compatibility between the thermodynamically unfavorable isomerization and hydroboration was the key factor in achieving convergent transformation.

Spread of Puumala Hantavirus to New Areas in a Large Croatian Outbreak of Hemorrhagic Fever with Renal Syndrome, 2021.

Background: The largest documented outbreak of hemorrhagic fever with renal syndrome occurred in Primorje-Gorski Kotar County, Croatia, in 2021, marking the first-time cases of hantavirus infection recorded outside of the known endemic region in the north of the county. Aim: To identify the factors contributing to the spread of the outbreak and to compare risk factors for acquiring hantavirus infection in the endemic and newly affected regions. Methods and Results: A total of 189 cases were confirmed by positive Puumala IgM/IgG antibodies (93.6%), and 13 probable cases were identified by clinical and epidemiological data (6.4%) using a structured questionnaire. Of the 179 cases with available clinical data, 59 (33.0%) were hospitalized. Three cases received hemodialysis, and no deaths were reported. Among 170 cases with information on exposures, 66 (38.8%) reported occupational risk. Cases in the northern part of county were more likely to have been infected in early spring (OR 27.1, 95% CI 2.93-250.7), to report seeing a rodent (OR 6.5; 95%CI 2.3-18.4), and to know someone with hemorrhagic fever with renal syndrome (HFRS) (OR 3.0; 95%CI 1.2-8.0) than cases from the southern part of the county. Data from Croatian Forests Ltd. suggested that an unusually good production of beech seeds in 2020 may have contributed to an increased rodent population in 2021. However, average temperature, rainfall, and humidity data from 2021 did not illustrate a significant difference from previous years (Kruskal-Wallis p = 0.837, p = 0.999, p = 0.108). Conclusion: The 2021 HFRS outbreak was likely fueled by an abundant rodent population and virus transmission in rodent hosts. Human activity, environmental factors, and the ensuing animal-human interactions have spread hantavirus infection from Croatia's mountainous region to a previously nonendemic coastal area with a Mediterranean climate.

Impact of Employee Environmental Concerns on Sustainable Practices: Investigating Organizational Commitment and Job Satisfaction

Environmental issues are gradually increasing due to increases in carbon emissions, overproduction, plastic use, the burning of fossil fuels, etc. Therefore, ecological sustainability is a primary concern for society and the upcoming generation. Considering this, the present research objective is to examine the factors influencing employee eco-friendly behavior (EEBH) and firm environmental performance (FEP). Cross-sectional data were accumulated from 403 employees working in casual dining restaurants in China and analyzed through partial least squares structural equation modeling (PLS–SEM) approaches (i.e., PLS algorithm, bootstrapping, blindfolding, and PLS prediction). The findings support the significant effect of environmental concern (ENVC) on employee organizational commitment (EOC), employee job satisfaction (EJoS), and EEBH. In addition, EOC and EJoS directly and indirectly influence EEBH. Furthermore, EOC also mediates the link between ENVC and EJoS. Finally, the findings also show that EEBH stimulates environmental performance. By showing the links between these elements, it has been emphasized that EEBH is a precondition of good organizational productivity and how it contributes to enhancing the EJoS and overall firm’s health. It challenges managers to create a work environment that is conducive to sustainability for improved customer relations and a strong reputation for the organization in society.

Pengaruh Membangun Budaya Organisasi dalam Meningkatkan Produktivitas untuk Memenuhi Kepuasan Pelanggan CV Family Group Kerupuk Jangek

This community service aims to determine the effect of building organizational culture in increasing productivity to meet CV Family Group customer satisfaction. Organizational culture has an influence on increasing the productivity produced by employees. Good productivity greatly determines customer satisfaction. The problems found when conducting research were: uncertain supply of raw materials, less strategic location, and many competitors who have similar businesses. The solution to this problem is to look for other suppliers so that there is no shortage of raw materials, the products produced must always be of good quality and taste good so that customers are satisfied and the business is able to compete in market share. This article was prepared by observation, collecting data in interviews, and documentation. The results of this research show that customer satisfaction depends on the products produced and the services provided by employees.

Sugar Replacement in Chocolate-Flavored Milk: Differences in Consumer Segments’ Liking of Sweetener Systems Relate to Temporal Perception

Chocolate-flavored milk contributes to excessive intake of added sugars among children and adolescents, which why it is a good candidate product for sucrose replacement. This study investigates how replacing sucrose partially or completely with different sweetener systems affects the sensory profile and consumer liking. Five chocolate-flavored milk treatments were formulated, varying in sucrose replacement level (partial: 58%; complete: 100%) and sweetener system (synthetic: acesulfame-K; natural: rebaudioside M-erythritol blend). Relative-to-Reference Scaling by a trained panel confirmed that no significant differences in the sensory profile when partial sucrose replacement was compared to sucrose, whereas the complete replacement increased bitter taste, pungent flavor, licorice flavor and mouth-drying. A total of 104 consumers evaluated the treatments for liking and indicated their temporal perceptions with temporal check-all-that-apply. Latent variable clustering performed on liking ratings revealed two clusters, which perceived temporal sensory characteristics differently depending on the sweetener system. Cluster 1 preferred the sucrose control over treatments with complete and partial replacement using a natural sweetener system, with complete replacement being perceived as having off-flavor. Cluster 2 preferred the sucrose control over partial and complete replacement using either of the sweetener replacements investigated, which were characterized as off-flavored and bitter. Understanding these consumer segments enables the food industry to develop effective low-energy formulations using synthetic and natural non-nutritive sweeteners, leading to reduced sugar consumption.

Export Performance Analysis on Indonesian Yellowfin Thunas (HS 030342) in the United States Market

Tuna is a major fish commodity that has high economic value that dominates the export market of Indonesian fishery industry products. This study was carried out to analyze competitiveness, comparative advantage, trading patterns and trends of Indonesian tuna exports in the United States market from 2013-2022 using the Revealed Comparative Advantage (RCA), Revealed Symmetric Comparative Advantage (RSCA), and Constant Market Share (CMS). The results showed that Indonesia's RCA value is above one (>1) during the 2013-2022 period, meaning that Indonesian tuna has competitiveness, the RSCA value is also above one (>0), meaning that Indonesian tuna has a comparative advantage. According to the CMS analysis, Indonesia’s growth of standard exports to the United States is still lower than the growth of world standard exports to the United States so that Indonesia's export performance is still relatively low. The distribution effect of the Indonesian tuna market shows a positive value which means that Indonesia has succeeded in showing good product distribution performance to the market. The effect of commodity composition and the effect of competitiveness of Indonesian tuna shows a negative value so that Indonesia is considered to have not met the market and is less competitive.

A Study on GAN-Based Car Body Part Defect Detection Process and Comparative Analysis of YOLO v7 and YOLO v8 Object Detection Performance

The main purpose of this study is to generate defect images of body parts using a GAN (generative adversarial network) and compare and analyze the performance of the YOLO (You Only Look Once) v7 and v8 object detection models. The goal is to accurately judge good and defective products. Quality control is very important in the automobile industry, and defects in body parts directly affect vehicle safety, so the development of highly accurate defect detection technology is essential. This study ensures data diversity by generating defect images of car body parts using a GAN and through this, compares and analyzes the object detection performance of the YOLO v7 and v8 models to present an optimal solution for detecting defects in car parts. Through experiments, the dataset was expanded by adding fake defect images generated by the GAN. The performance experiments of the YOLO v7 and v8 models based on the data obtained through this approach demonstrated that YOLO v8 effectively identifies objects even with a smaller amount of data. It was confirmed that defects could be detected. The readout of the detection system can be improved through software calibration.

Comprehensive in vitro and in silico Evaluation of Safety and Probiotic Potential of Lactiplantibacillus plantarum strain LFN10

ABSTRACT The study aimed to assess the safety and probiotic potential of strain Lactiplantibacillus plantarum LFN10, isolated from Algerian fermented milk “Lben,” using genome-sequencing and in vitro approaches. Safety assessments revealed LFN10 as negative for virulence and antibiotic resistance. With favorable physiological and biochemical traits, a versatile carbohydrate metabolism and good exopolysaccharide production abilities, it qualifies as nonstarter culture for food fermentation. The strain displayed resilience to acidic and bile salt stress and exhibited strong cholesterol-lowering capabilities. The moderate interaction with pathogens suggests its potential ability to inhibit them. The strain also demonstrated inhibitory effects on foodborne pathogens. Whole genome sequencing and bioinformatics analyses facilitated taxogenomic classification and confirmed the presence of stable chromosomal marker genes associated with probiotic and technological functional qualities. Overall, LFN10 appears as a promising candidate for application as probiotics, which requires further in vivo studies to confirm its safety and efficacy as well as to optimize its application in food and as nutraceuticals.

3 + 2] Cycloaddition Reaction of Vinylsulfonium Salts with Hydrazonoyl Halides: Synthesis of Pyrazoles.

An efficient [3 + 2] cycloaddition reaction between in situ generated nitrile imines from hydrazonoyl halides and vinylsulfonium salts is developed. The nitrile imines are demonstrated to be a new class of reaction partner for vinylsulfonium salts to conduct the [3 + 2] cycloaddition reaction. The process provides a concise and efficient method for the construction of pyrazole derivatives under mild reaction conditions with broad substrate scope, good product yields, and high regioselectivity.

Brain targeting efficacy of novel drug delivery system in the treatment of Alzheimer's disease.

Alzheimer's disease (AD), a common degenerative disease of the central nervous system in the elderly, has become the third largest health killer after cardiovascular and cerebrovascular diseases and tumors. Based on the fact that Alzheimer's disease is a disease with multiple etiologies and complex pathology, a single target is bound to have a limited curative effect, and the synergy of multiple links and multiple targets is expected to achieve a better curative effect. The aim of this study is to investigate the brain targeting of a drug modified by chitosan, based on the new nanodrug delivery system for treating Alzheimer's disease developed by the research group. Chitosan with good biocompatibility, biosorption, and degradation products that can protect and promote the regeneration of nerve cells was selected to combine with galantamine, a natural representative cholinesterase inhibitor, to develop a new nano drug delivery system for nasal delivery of anti-Alzheimer's disease with a multi-target synergistic effect. Synchronous analysis was conducted on the blood and brain tissue drug concentrations after intravenous and nasal administration of the original drug solution and system solution. The brain targeting index (DTI) is used to evaluate the brain targeting effect of the nano-drug delivery system after intranasal administration. The blood concentration of galantamine original drug solution and galantamine system solution after intravenous injection and nasal show that in the two administration methods of intravenous injection and nasal administration, under the same administration method, the time point of the system reaching the highest blood drug concentration is much higher than that of the original drug. The content of galantamine in plasma samples and tissue samples indicate that after intravenous administration and intranasal administration of the galantamine system, at the same time point, the drug concentration in brain tissue was far greater than that of the original drug of galantamine, and the duration was also longer. The concentration of drugs in brain tissue decreased gradually in the order of olfactory bulb, olfactory tract, brain, and cerebellum. In the brain tissues of the olfactory bulb, olfactory tract, cerebrum, and cerebellum, the drug concentration of the galantamine system after intravenous injection is lower than that after nasal administration. This study concludes that compared with the original drug solution, the nano drug delivery system has significant brain targeting for nasal administration, and intravenous injection also has brain targeting. In the olfactory bulb, olfactory tract, brain, and cerebellum, the brain targeting index at the olfactory bulb is the highest, and the targeting is the best.

An Improved Method of Good Quality Shidol Production in the Northern Part of Bangladesh: from Biochemical and Microbiological Aspects

An Improved Method of Good Quality Shidol Production in the Northern Part of Bangladesh: from Biochemical and Microbiological Aspects

Unveiling a Novel Antidote for Deoxynivalenol Contamination: Isolation, Identification, Whole Genome Analysis and In Vivo Safety Evaluation of Lactobacillus rhamnosus MY-1.

Deoxynivalenol (DON) is a global contaminant found in crop residues, grains, feed, and animal and human food. Biodegradation is currently the best solution for addressing DON pollution. However, efficient detoxification bacteria or enzymes that can be applied in complex matrices are lacking. The aim of this study was to isolate a DON-detoxifying probiotic strain with a high degradation rate, a good safety profile, and a clear genetic background. One hundred and eight bacterial strains were isolated from 300 samples collected from a school farm and surrounding livestock farms. A new DON-degrading strain, Lactobacillus rhamnosus MY-1 (L. rhamnosus MY-1), with a degradation rate of 93.34% after 48 h and a comprehensive degradation method, was identified. Then, MY-1 at a concentration of 1 × 108 CFU/mL was administered to mice in a chronic intoxication experiment for 28 days. The experimental group showed significantly higher weight gain and exhibited good production performance compared to the control group. The length of the ileal villi in the experimental group was significantly longer than that in the control group. The expression of pro-inflammatory cytokines decreased, while the expression of anti-inflammatory factors increased in the experimental group. Whole-genome analysis revealed that most of the MY-1 genes were involved in carbohydrate metabolism and membrane transport, with a cluster of secondary metabolite genes encoding antimicrobial properties. In summary, this study successfully identified a Lactobacillus strain with good safety performance, high DON degradation efficiency, and a clear genetic background, providing a new approach for the treatment of DON contamination.

Cognitive Factors Leading to Human Error: A Major Contributing Factor for Quality Deviations in Pharmaceutical Industry

The pharmaceutical sector is one of the top research-based sectors in the world which continuously produces new medications that improve and save human lives. Patients, as well as healthcare professionals depend on pharmaceutical companies for the treatment of ailments, so it is very important to develop a good quality product following Good manufacturing practices guidelines that ensure the quality, safety, and efficacy of the product. Human cognitive errors are a major cause of quality deviations. These quality deviations result in product recalls, a ban on products by regulators where the company’s reputation will be tarnished which can result in loss of sales and revenue. Human errors can be identified and mitigated by various techniques. In this paper, we discuss the factors contributing to cognitive errors, the impact of cognitive errors on the pharmaceutical industry, the identification of the cognitive errors causing current good manufacturing practices (cGMP) deviations, and challenges in the mitigation of cognitive errors. A survey questionnaire and the form human error assessment and reduction technique (HEART) tool were also developed and discussed in the manuscript.

Analisis Bauran Pemasaran dalam Meningkatkan Daya Beli Konsumen (Studi Kasus pada Batik Mirabella di Kecamatan Simpang Pulai Jambi)

The Marketing Mix is ​​known as 4P and has components, namely product, price, place and promotion. Mirabella Batik Shop, Jambi City is a business that operates in the field of selling genuine Jambi batik and batik from outside Jambi or from Java. Various types of batik materials such as handloom, silk, semi-silk, sanwos, cotton, semi-written. And types of motifs such as Angso duo, Kapal Sangat, Durian Pecah, Tampuk Manggis and Kopi. This Mirabella batik shop is very good with good quality products. The problem faced by the Mirabella Batik Shop in Jambi City is that sales have decreased in sales volume, the marketing strategy looks good but it is difficult to attract consumers. Mirabella Batik Shop, apart from using social media to promote its products, the batik shop also uses a Word of Mouth (WOM) system, which can be called word-of-mouth promotion. This research aims to determine the application of marketing mix analysis in attracting consumer buying interest in Mirabella Batik, Jambi City. The location of this research is located on Jalan Sultan Agung No. 21 Rt 16/02 Kel. Pure District. Telanalpura Simpang Pulai, Jambi City. This research is a qualitative descriptive research, because it aims to describe the conditions and phenomena in the field at the Mirabella Batik Shop, Jambi City and uses data collection techniques in this research, namely interviews, observation and documentation. The data source in the research is primary data from interviews with shop owners, shop employees and consumers. And secondary data from books and journals. The research results show that there are 4 marketing mixes carried out by the Mirabella Batik Shop in Jambi City, namely Product, Price, Place and Promotion. The influence on the Marketing Mix at the Mirabella Batik Shop, Jambi City, the product quality is very good, but attracting consumers is very difficult due to competitiveness in other shops.

The Development of HOTS Questions Based on Ethnomathematics to Measure Students' Mathematical Problem-Solving Abilities

The research aims to develop ethnomathematics-based Higher Order Thinking Skills (HOTS) questions to measure students' problem-solving abilities. This research uses a research and development (R&D) method with an ADDIE model, which consists of five stages, i.e., analysis, design, development, implementation, and evaluation. The subjects in this research were 30 class VIII students at SMP Negeri 1 West Sorkam. Research instruments include expert validation questionnaires, student response questionnaires and tests of students' mathematical problem-solving abilities. The research data were analyzed using quantitative descriptive methods by determining the average achievement value of the products developed. The experts' assessment shows that the product developed has a score of 84.6 with the criteria "Very Valid". Based on the results of the questionnaire, students' responses to HOTS questions based on ethnomathematics were seen from the practical aspect with a score of 77.63 in the "Practical" criteria and the results of tests on students' mathematical problem-solving abilities obtained an average score of 75.22 so that the product developed met the "effective" criteria. So it can be concluded that the development of ethnomathematics-based HOTS questions on geometric material produces a good product and is suitable for measuring students' mathematical problem-solving abilities.

HAND SOLDERING PROCESS TRAINING MATERIAL USING ADDIE APPROACH TO SUPPORT E-LEARNING IMPLEMENTATION IN XYZ COMPANY

Training is very important to increase the productivity of the company. Without the right training, worker will not understand and not know how to do right process. Worker with right process will be achieve good product. Sometimes, the problem of lack training is no proper training material availability for process. In this paper, author want to create training material for soldering process because soldering process is one of critical process, no proper soldering training material and support e-training as new implementation in XYZ company, and author is using ADDIE approach to create it. From ADDIE approach, author create 2 training phase and 2 types of assessment and training use multi – sensory learning which are visual, auditive, kinesthetic and tactile. In visual, using interactive video, participants watch the video, do the process as they see in the video, give the explanation, and they can ask the trainer if any question. Then worker will get training more about product especially for quality, output and ergonomic. After implementing it, workers is more understand and they can produce good product and right quantity, and trainer is more comfortable to give training for workers.

Pengaruh Kualitas Pelayanan terhadap Kepuasan Pelanggan di Hotel Pyramid Suites Banjarmasin

Banjarmasin is a unique city nicknamed the City of a Thousand Rivers. This uniqueness is what causes many entrepreneurs to come to open businesses, one of which is a hotel business. The recommended hotel in Banjarmasin is the Pyramid Suites Hotel. Because apart from having good quality products and services, this hotel has also received many awards from various online hotel booking applications. Therefore, researchers are interested in further researching the Pyramid Suites hotel in Banjarmasin with the aim of analysing the influence of service quality on guest customer satisfaction at the Pyramid Suites Banjarmasin hotel. This study aims to analyse and describe how much influence service quality has on customer satisfaction. This type of research is quantitative, with a conclusive causal approach, namely research that aims to obtain a conclusion from the data that has been obtained and processed which explains the causal relationship between the variables. The population in this study are members of Hotel Pyramid Suites, namely guests who stay more than three times. research sample as many as 100 respondents. The data collection technique used a questionnaire which was then used as a score tabulation for each variable studied. The data analysis method used in this study is Smart PLS 3. The results showed that the quality of service which consists of variables of physical evidence, reliability, responsiveness, assurance and empathy affect customer satisfaction.

FePO4.2H2O recovery from acidic phosphate-rich waste streams

Phosphorous not only needs to be removed to prevent eutrophication of wastewater effluent receiving surface water bodies, but it also has to be recovered as a scarce finite reserve. Phosphorus chemical precipitation as NH4MgPO4·6H2O, Ca3(PO4)2, or Fe3(PO4)2 ·8H2O is the most common method of phosphorus recovery from phosphorus-rich streams. These minerals ideally form under neutral to alkaline pH conditions, making acidic streams problematic for their formation due to the need for pH adjustments. This study proposes FePO4 .2H2O (strengite-like compounds) recovery from acidic streams due to its simplicity and high efficiency, while also avoiding the need for pH-adjusting chemicals. The effect of initial pH, temperature, Fe (III) dosing rates, and Fe (II) dosage under different oxidation conditions (pO2 = 0.2, 1, 1.5 bar, different H2O2 dosing rates) on phosphorus recovery percentage and product settleability were evaluated in this study. The precipitates formed were analyzed using optical microscopy, SEM, XRD, SQUID, Raman, and ICP. Experiments showed that Fe (III) dosing achieved phosphorus recovery of over 95 % at an initial pH of 3 or higher, and the product exhibited poor settleability in all initial pH (1.5-5), and temperature (20–80 °C) tests. On the other hand, Fe (II) dosage instead of Fe (III) resulted in good product settleability but varying phosphorus recovery percentages depending on the oxidation conditions. The novelty of the study lies in revealing that the Fe (II) oxidation rate serves as a crucial process-design parameter, significantly enhancing product settleability without the requirement of carrier materials or crystallizers. The study proposes a novel strategy with controlled Fe2+-H2O2 dosing, identifying an Fe (II) oxidation rate of 4.7 × 10−4 mol/l/min as the optimal rate for achieving over 95 % total phosphorus recovery, along with excellent settleability with a volumetric index equal to only 8 ml/gP.

PERAN BADAN USAHA MILIK DESA DALAM PENGEMBANGAN EKONOMI LOKAL MELALUI KEWIRAUSAHAAN SOSIAL

The purpose of this dedication activity is to improve the well-being of the people of Gegarang village with the role of the village owned enterprise agency as a driver and create creative and innovative social entrepreneurship. The approach of this dedication activity is Participatory Action Research (PAR). The results of this dedication show that (1) participants have an understanding of social entrepreneurship and marketing, (2) participants have successfully implemented the process of making onion cakes based on Fish Depik good taste and good product packaging, (3) the success rate of dedication activity seen from the large number of consumers who purchased the product.