Continuing our journey after the golden jubilee year of Journal of Software: Practice and Experience (SPE), this January 2022 issue focuses on new trends in computer science and software engineering. There are several emerging trends in the computer science, and software development landscape is growing by venturing into and adapting new technologies. Blockchains are being used in different domains for ensuring data security and retaining data provenance. Machine learning is extensively being used in different domains for solving relevant problems; software innovation is no exception. Continuous integration is driving the software development process in the industry. The Internet of Things (IoT) and real-time applications are becoming ubiquitous and are going green. Quantum computing is catching significant attention and first simulators and experimental testbeds are being provided, for the community to venture into the domain. It is time that SPE also looks into the ongoing developments and brings forth the practice and experience of the research community. Going by the motto, this issue starts with a research paper that dealt with blockchains for protecting data confidentiality and traceability. The issue has several research papers related to software engineering such as acquiring cross-domain requirements, just-in-time defect prediction, and benchmarking garbage collection delays. The issue also has papers relevant to cloud computing and wireless sensor networks, with specific focus at energy efficiency. Several of these research works have applied machine learning for achieving relevant research goals. The issue also has a paper that summarizes the state-of-the-art in software effort estimation using machine learning techniques. The issue concludes with a systematic review of quantum computing along with discussion on future research directions. The new EAB members include both established and emerging researchers who have a good track record and are associated with SPE in several ways including publishing their own high-quality research papers and/or organizing special issues on emerging topics. They are drawn from all over the world recognizing growing submissions for SPE from all regions. We request EAB, authors, reviewers, and readers for their continued support in sustaining SPE as the premier forum for publishing new software research and innovation along with practice and experience focus. Your feedback and comments on further improving SPE are highly appreciated.