This article explored the link between medicine and sharing the message of Jesus in Ghana. It looked at how medical missions and medical evangelism have played a vital role in bringing both physical healing and spiritual hope to people in need. It also analyzed developments and progress associated with modern medicine and its usage by the church to foster the well-being of Ghanaians. By creating hospitals, clinics, and other healthcare services, churches in Ghana have made a big difference in the lives of those who are often forgotten or lacking medical care. The article focused on three main churches—the Catholic Church, the Presbyterian Church of Ghana, and the Methodist Church, Ghana—and their contributions to holistic ministry over time. The research adopted the qualitative historical approach within the framework of practical theology as the methodology for the study. Primary data was gathered through historical documentation, personal interviews and the researcher’s participation in the missions field as a volunteer. Secondary data were sourced from peer-reviewed articles and books. The research revealed how these churches have combined their faith with their desire to help others, bringing medical assistance and spreading the love of God in the process. By understanding the important role of medical missions, their connection to sharing the Gospel, and the reason why the pioneering missionaries added it to their missions, readers will gain a deeper appreciation for the efforts of churches in Ghana and the impact they have on the lives of people in their communities. Keywords: Medical Missions, Medical Evangelism, Medivangelism, Social Action, Evangelism
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