Economic development is one of the main goals of states, state entities and unions. An important place in the development of the economy is to maintain and ensure competition. The legal order and forms of maintaining competition in state entities are different. At the same time, they are all aware of the high public danger of anti-competitive agreements. In this connection, the legislation of most countries and unions (organizations) provides for the prohibition of anti-competitive agreements and serious measures of prosecution for their conclusion. The aim of the work is the author's analysis of the international legal approach to the regulation of liability and prosecution of persons (both legal and physical) for the conclusion and participation in anti-competitive agreements. In this work, the methods of logical and analytical analysis of the legislation of countries, international organizations and unions were used. According to the results of the study, it can be concluded that the importance (and hence the danger of cartels) of combating anti-competitive agreements is understood in most countries with leading economies. This danger is recognized both at the level of the state itself and at the level of state unions and organizations. The international community pays great attention to the issue of competition. The competition law of developed countries and international organizations in which they are composed is a developed system of effective regulation. In order to optimize the interaction of law enforcement agencies and agencies involved in the fight against cartels, it is necessary to create common information bases, regulate the exchange of documents and information. In our opinion, it seems necessary to develop and implement the institute of joint activities by foreign agencies.