The use of a new, insoluble polymer-bound bis(oxazoline) ligand (IPB–box) for the copper-catalyzed heterogeneous enantioselective glyoxylate–ene reaction is described. Good activity and ee values in the range 85–95% have been obtained during five to seven recycles, either in batch mode or under flow conditions, demonstrating also the recovery and reuse of the whole catalytically active copper complex.