Introduction: An educational intervention strategy was carried out in the teaching-learning process of the discipline of Pharmacology and Clinical Pharmacy at the Jean Piaget Polytechnic Institute of Benguela in the Republic of Angola, prior to an initial diagnosis of the process, and the perception of the level of satisfaction of students and teachers was intended to be analyzed.Objective: to evaluate the level of overall satisfaction regarding the improvement of the Teaching and Learning Process in the discipline of Pharmacology and Clinical Pharmacy.Method: A descriptive and cross-sectional observational study was carried out with a quantitative or positivist approach. A questionnaire was applied to 8 teachers and 43 students. 28 variables were analyzed (15 for teachers and 13 for students). The Global Satisfaction Index was calculated through the Iadov technique.Results: the Iadov Global Satisfaction Index (ISG) was 0.63 and 0.57 for teachers and students respectively. According to the interpretation of this result, it is within the range of satisfactory evaluation. According to the professors' evaluation, low indices were obtained in the range of lack of definition in learning through clinical cases (ISG=0.44) and the topic of teaching based on experimentation (ISG=0.44). On the part of the students, the variable that generated dissatisfaction in them was the experimentation activities in any of its modalities [ISG= (-0.05)].Conclusions: Overall, there is satisfaction in students and professors with the modifications implemented in the educational teaching process in the discipline of Pharmacology and Clinical Pharmacy