PurposePracticing oral habits beyond the normal age range is assumed to be due to underlying psychological disturbance and could result in a deformation of the orofacial structure. The first step in managing such a health condition is to evaluate its size. Thus, this study aimed primarily to assess the prevalence of oral habits among a group of school children aged from 5 to 7 years, in Cairo, Egypt. The secondary aim of the study was to investigate some possible related predictors along with the mother’s perception of the child’s oral health-related quality of life.MethodsA Google form questionnaire was designed, utilizing the third domain of Nordic Orofacial Test-Screen (NOT-S), to assess the presence or absence of oral habits and their types, if reported. Also, there were two global rating items to test the child’s oral health-related quality of life from the mother’s prospection, along with one item to inquire if the mother thinks that the oral habits are harmful to the child. A total number of 23 schools in Cairo, Egypt were randomly selected, and the link to the Google form was distributed through the parent’s groups on social media. All high-quality complete responses were analyzed using the SPSS program, and a Log-binomial regression model was constructed, to determine the significant predictors of practicing oral habits in children.ResultsAmong the analyzed 1128 responses, the total number of answers to the third domain of interview part of NOT-S was 1235, with a response rate of (60.39%), no habits were reported in 635 children (51.4%), while nail biting was noted in 21.8%, bruxism in 17.9% and Sucking habits in 8.9%. In total, 63.8% of children who were reported by their parents to be the “only child” didn’t practice any habit, and a higher prevalence of oral habits was detected in children with siblings. There was no detectable association between the mother’s educational level and practicing any of the habits, although there was an association between the mother’s educational level and their awareness of the harmful effect of oral habits on the child. The mothers’ answers to the global rating items were not associated with any of the oral habits.ConclusionThe most prevalent oral habit in the current study was the nail-biting habit. The presence of other siblings and the number of siblings were contributory factors in the occurrence of oral habits, while mothers’ educational level was not associated with practicing oral habits. The mothers’ awareness of the harmful effect of oral habits on the children was not satisfactory, and there was no association between oral health-related quality of life and the children’s oral habits, from the mothers’ perspective.