Cloud seeding is well known to address water shortage problems caused by droughts by adding more precipitation and consequent runoff. Unlike previous studies, this study investigates another positive effect of cloud seeding on the activation of vegetation by integrating numerical cloud seeding simulations and processed-based modeling of various ecohydrological components. As the carbon cycle is closely related to the hydrological processes in ecosystems, we adopt the RHESSys ecohydrological modeling to synthetically simulate runoff and soil moisture along with primary productivity and vegetation respiration. Numerical simulations with and without cloud seeding are generated by the WRF-ARW model for the Boryeong Dam basin, one of the basins vulnerable to droughts, in 2021. The cloud seeding simulations of two cases are input into the RHESSys model to examine changes in hydrological and ecological components due to the added amount of precipitation. The results exhibit significant increases in annual precipitation (18 %) and runoff (22 %), and enhanced soil moisture stimulating the ecological components such as GPP and NPP, especially in spring. Cloud seeding can be considered to create optimal conditions for vegetation to absorb or sequester carbon from the atmosphere, thereby boosting vegetation growth. Additionally, the time-lagged correlations between cloud seeding and soil moisture, GPP, NPP, and respiration suggest that vegetation activity is highly dependent on antecedent 1–2 months occurrences of cloud seeding. This study implies that the cloud seeding effect on additional NPP can be considered as a countermeasure of the global average forest loss, which means that carbon emission rise in the global warming era can be partly alleviated by cloud seeding.