BackgroundThe role of blood flow in the pathogenesis of glaucoma is not well understood.ObjectiveTo discuss applications of OCTA in glaucoma diagnosis and management.MethodsReview of literature and presentation of ongoing clinical trials.ResultsMore than 50 peer‐reviewed publications on OCTA in glaucoma are available. Data demonstrate good reproducibility and repeatability of OCTA measurements in glaucoma patients. Good correlation to structural and functional measures of glaucoma have also been found. Preliminary data have not found a demonstrated effect of IOP‐reduction of OCTA‐derived vessel density measurements. At present, studies on the long‐term role of OCTA in glaucoma evaluation are ongoing.ConclusionsOCTA measurements of vessel density in glaucoma are reliable. Good correlation to structure‐function has been demonstrated. Available data suggest a role of OCTA for better understanding of the pathophysiological processes in glaucoma. It is unclear, at present, how this technology can be integrated into the long‐term management of glaucoma patients.