This prospective clinical study aimed to clinically investigatethe efficiency of (GIC) glass-ionomer cement application (Ionostar Plus + Easy Glaze, VOCO) in reducing hypersensitivity in permanent molars affected by molar incisor hypomineralisation when assessed immediately (15 min) and 12 weeks after its application. Children with at least one hypersensitive MIH-affected permanent molar (MIH-TNI-3 or 4). The pre-treatment status was evaluated and only included if they did not receive a tooth-specific in-office desensitizing treatment within one month. Clinical pain assessments were performed using the schiff score air sensitivity scale (SCASS) and Wong-baker faces Scale (WBFS). This study involved 25 participants (mean age 8.6 ± 1.85 years) with 43 hypersensitive MIH-molars of which about half were SCASS 3 (n = 24, 55.8%) and SCASS 2 (n = 19, 44.2%). Regarding hypersensitivity, the reported mean SCASS score reduced significantly from 2.56 (± 0.50) at baseline to 1.14 (± 0.96) after 15 min of GIC sealant application and even further to 0.71 (± 0.89) after 12 weeks (P < 0.001, Pairedttest). Similarly, reported WBFS scores also significantly reduced from 5.81 (± 2.50; Range = 2-10) at baseline to 2.88 (± 2.31; Range = 0-10) after 15 min and to 2.95 (± 2.17) after 12 weeks, respectively (P < 0.001, Pairedttest). The mean reduction in SCASS scores was 1.3 (± 0.6) and 1.4 (± 1.0) for baseline SCASS 2 vs. 3, respectively. GIC coverage is effective in providing clear instant relief from hypersensitivity in MIH molars in schoolchildren, which improves even further over a period of 12 weeks.
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