Giant Meningioma Research Articles

Giant Nondural-Based Cauda Equina Meningioma with Multiple Cysts

A very rare case of a giant nondural-based cauda equina meningioma with multiple cysts was presented. Spinal meningioma most commonly occurs in the thoracic or cervical region and typically adheres to the dura. Only six cases of nondural-based meningioma have been reported in English literature. All occurred in the cauda equina region. These patients were predominantly female and younger than those with typical intraspinal meningioma.A 46-year-old woman had a 4-year history of lower back pain and right leg pain. Progressive weakness of both lower extremities occurred. Magnetic resonance imaging revealed a giant cauda equina tumor with multiple cysts from T(12) to L(4). Following laminectomies from T(11) to L(5) and intradural exposure, the tumor was found to be draped loosely by the roots of the cauda equina and attached to a root without any firm connection with dura mater. Complete removal of the tumor was achieved after microdissection of arachnoid and sacrifice of an involved rootlet of the cauda equina. The appearance of tumor was that of a typical neurilemmoma. However, histological and immunohistochemical analyses were consistent with meningioma. Nondural-based intraspinal meningiomas are very rare, particularly a giant tumor with multiple cysts as our presenting case. All of the cases previously reported, including our case, have been located in the cauda equina region. Most of the patients were female and were young, suggesting that the nondural-based cauda equina meningiomas are age- and sex-related. An accurate preoperative and operative diagnosis are difficult. Care must be taken in the management of cauda equina tumors resembling neurilemmoma which may in fact represent meningioma, particularly in the younger female.

Microsurgical treatment for large and giant meningiomas of the cerebellopontine angle

目的 探讨桥小脑角大型及巨大型脑膜瘤手术入路及显微手术切除方法. 方法回顾分析经显微手术治疗的28例桥小脑角大型及巨大型脑膜瘤.其中19例采用枕下乙状窦后入路,3例采用颞枕开颅乙状窦前入路,4例采用颞枕开颅颞下小脑幕入路,2例采用颞枕开颅与幕上、下联合入路. 结果肿瘤全切除(Simpson Ⅰ、Ⅱ级)22例,全切除率为78.6%.全组无手术死亡.术后症状改善者20例,症状基本同术前5例.26例随访6个月至4年,生活自理者23例(88.5%),复发2例(7.7%). 结论合理选择手术入路,术中应用显微技术妥善处理和保护血管、神经、脑干等,能较理想地切除肿瘤和提高患者生存质量。

Giant olfactory groove meningiomas: advantages of the bilateral fronto-orbitonasal approach.

Olfactory groove meningiomas are usually considered surgically curable, but the operation becomes complex when the tumour reaches massive size and involves vital suprasellar structures, extends into the ethmoid sinuses or extensively involves the bony floor of the anterior fossa. The traditional bifrontal approach provides only limited exposure in these situations, and a bilateral fronto-orbitonasal approach may be more effective. We reviewed our experience in five patients with resections of massive olfactory groove meningiomas to assess the advantages and risks of these two approaches. All patients were women (mean age, 45 years; range, 28-59) presenting with symptoms and signs related to increased intracranial pressure, cranial nerve impairment or brain compression. Computed tomography, magnetic resonance imaging and cerebral angiography were used for diagnosis and operative planning. The approach was bifrontal in two patients and bifronto-orbitonasal in three. Total surgical removal (Simpson grade I, three patients; Simpson grade II, one patient) was achieved in four patients (80%) and subtotal tumour removal (Simpson grade III) was performed in one (20%). One patient had two staged operations. No morbidity or mortality occurred in this series. No clinical or radiologic evidence of recurrence developed in the four patients whose tumour was resected totally. The bilateral fronto-orbitonasal approach resulted in safe and successful total removal of giant olfactory groove meningiomas, achieving long-term prevention of recurrence. We highly recommend this approach. Copyright 1999 Harcourt Publishers Ltd.

Giant occipital intracranial and extracranial meningioma

Giant occipital intracranial and extracranial meningioma

Combined transpetrosal and fronto-orbito-zygomatic approach to a giant skull based meningioma: a case report

BACKGROUND Recently, various surgical approaches to skull base lesions have been developed. Skillful use of the combination of two standard approaches make possible the removal of large brain lesions, which conventionally had been considered inoperative. In this study, we present a case of a giant meningioma located in the cerebellopontine angle and middle cranial fossa. A near total resection was achieved using a combined transpetrosal and fronto-orbito-zygomatic approach. CASE REPORT A 15-year-old boy presented with a meningioma that caused a left hearing loss, dysarthria, and cerebellar ataxia. Preoperative magnetic resonance imaging revealed a giant meningioma located in the right cerebellopontine angle, middle fossa, and cavernous sinus. The patient underwent a near total resection of the tumor through a combined transpetrosal and fronto-orbito-zygomatic approach. He experienced a marked improvement postoperatively and entered high school the following year. CONCLUSIONS An approach from several angles was necessary for the giant skull based tumor presented here. A combination approach was selected for obtaining a wide operative field with minimal brain compression during resection of neoplasm. According to the individual features of each case, selection of the operative approach, decisions regarding the extent of excision, and postoperative treatment regimens should be adequately planned in the preoperative period.

P-5-583 - Total removal of giant meningiomas

P-5-583 - Total removal of giant meningiomas

P-5-582 - Surgical management and outcome of giant meningiomas

P-5-582 - Surgical management and outcome of giant meningiomas

巨大髄膜腫に対する外科治療の問題点

巨大髄膜腫に対する外科治療の問題点

Giant Meningioma : Correlation between Tumor Volume and Clinical Manifestations

Giant Meningioma : Correlation between Tumor Volume and Clinical Manifestations

Dura and Cranial Base Reconstruction by External Oblique Fascia and Rectus Abdominis Muscle Flap

The rectus abdominis muscle flap, combined with the external oblique fascia, were utilized in cranial-base reconstruction. In a wide defect caused by resection of a giant meningioma, the dura was reconstructed with the external oblique fascia and anterior sheath, and the cranial-base defect was reconstructed with the rectus abdominis muscle flap.

A giant hyperostosing meningioma in a child

A case of 15-year-old boy with a giant hyperostotic meningioma is presented. The patient had a huge prominence at the posterior parietal region. The CT scan showed a giant intracranial tumor in the left parieto-occipital region under the hyperostotic bone. The tumor and hyperostotic bone were totally resected with the involved portion of the sagittal sinus. Histological study revealed a meningioma. The presence of such a huge hyperostosis and some peculiarities of childhood meningiomas are discussed.

Giant congenital meningioma in a newborn

The authors report the case of a giant meningioma in a 5-day-old newborn. Congenital meningiomas are extremely rare. Five newborns with meningiomas have been reported in the literature to date. This is the first case of a newborn with a giant meningioma with supra- and infratentorial and intraorbital components.

Giant meningioma in a fourteen-month-old infant

A case of giant meningioma in a 14-month-old infant is presented and pathologic characteristics of such lesions are reviewed.

Giant bilateral parasagittal fronto-parietal hyperostosing meningioma. Clinico-therapeutic considerations in a particular case

A case of giant bilateral parasagittal fronto-parietal hyperostosing meningioma is discussed. Its weight was 910 gr., it was removed in two operations and finally an acrilic cranioplasty was done. The patient pas followed for 24 years and no neurological sequelae have been found. He is still working as a farmer. The author reviews the relevant literature and discusses the differential diagnosis.