Bladder stones account for 5% of all urinary system stones. They are frequently observed in old males and occur secondary to prostatic hyperplasia, neurogenic bladder, or other infravesical obstructions. Generally, bladder stones can be discharged spontaneously, while larger stones may block urination, resulting in full obstruction causing acute urinary retention. Furthermore, large bladder stones can cause unilateral or bilateral ureterohydronephrosis, while they can rarely cause renal failure. In this manuscript, we present a case of an acute renal deficiency and urosepsis that developed due to a large bladder stone in a young male patient who used a permanent catheter after a spinal cord injury. After the cystolithotomy, the removed stone weight was 280 g with a size of 5.5x4.2x3.6 cm. It should always be considered that very large bladder stones may render fatal clinical outcomes, though rarely. We aimed to emphasize the importance of periodic urinary system follow-up of patients with spinal cord injury.
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