Development and Validation of the Patient Satisfaction with Sedation Instrument (PSSI) Dennis Revicki, John J. Vargo, Kellee Howard, Jennifer Petrillo, John Mcrorie Background: Patient reported outcome measures are needed to evaluate satisfaction with sedation delivered during gastrointestinal endoscopic procedures. Currently there are no validated or universally accepted patient satisfaction scores in use that are specific to endoscopic sedation. Methods: The PSSI was developed, based on patient focus groups and clinician input, to measure patient perceptions of satisfaction with sedation delivery associated with outpatient upper endoscopy and colonoscopy. The PSSI consists of 16 items covering 3 dimensions of sedation delivery, procedural recall and sedation side effects, and has 4 global satisfaction items. Items are rated on a 7-point Likert scale ranging from 1 (very satisfied) to 7 (very dissatisfied). Factor analysis was used to derive the final 16 item version. Internal consistency reliability was assessed and validity was assessed by examining the association between the PSSI scores with clinician satisfaction ratings, and the SF-12 Health Survey (PCS, MCS), Patient Satisfaction Questionnaire-18 (PSQ-18), and Social Desirability Rating Scale (SDRS) scores. Results: A psychometric evaluation study was conducted in 5 gastroenterology practices across the United States and included 118 patients who underwent elective colonoscopy or EGD. The study participants were mostly women (59%), white (88%), and with mean age of 57.5 G 15.7 yrs. Internal consistency reliabilities of PSSI total and subscale scores were all O0.86. The correlations between the PSSI total score and clinician rated satisfaction were moderate (r Z 0.21, p ! 0.05). The correlations between PSSI scores and MCS was (r Z 0.06 to 0.22, p O 0.05 to p ! 0.05) and the PCS was (r Z 0.24 to 0.27, p ! 0.05). PSSI total scores were correlated with PSQ-18 general satisfaction (r Z 0.29, p ! 0.05), interpersonal manner (r Z 0.24, p ! 0.05), and accessibility/convenience (r Z 0.30, p ! 0.01) scores, and PSSI scores were not significantly correlated with SDRS scores (r Z 0.01-0.08, p O 0.05). Conclusions: The PSSI is a reliable and valid measure of patient satisfaction with important areas, from the patient’s perspective, of sedation delivery during GI endoscopic procedures. This evaluative tool can be used to standardize patient assessment of procedural sedation satisfaction for outpatient colonoscopy and EGD in future sedation trials. S1573 Patient Satisfaction with Lower Gastrointestinal Endoscopy: Doctors, Nurses and Non-Medical Colonoscopists Sushil K. Maslekar, Graeme S. Duthie Aims: Colonoscopy is performed by doctors and nurses world-wide. We have now trained non-medical personnel to perform colonoscopy in order to overcome shortage of trained colonoscopists. The aim of this study was to prospectively determine patient satisfaction and factors that determine satisfaction with lower gastrointestinal endoscopy and to determine if there is a difference between nurses, non-medical and medical colonoscopists. Methods: Consecutive patients undergoing lower gastrointestinal endoscopy answered a validated patient satisfaction questionnaire at the time of discharge and 24-hours thereafter. All patients were blinded to the grade of the performing colonoscopists. Demographic, clinical and pathological data was prospectively collected and entered into SPSS software package. Multivariate regression analysis was done to determine factors influencing patient satisfaction. Results: A total of 400 patients (mean-age 61.8 years) were surveyed after lower gastrointestinal endoscopy. Examinations were performed by a nurse practitioner (n Z 110), doctor (n Z 149), or non-medical colonoscopists (n Z 141). There was no difference between three groups in terms of completion rates (p ! 0.001), duration of procedure (p Z 0.001), or rate of complications. No differences were detected between endoscopists in patient rating for overall satisfaction (p Z 0.6), technical skills of the endoscopist (p Z 0.58), communication skills (p Z 0.61) or interpersonal skills of the endoscopist (0.59). 96% of participants strongly agreed they would be willing to undergo another examination and 94.9% would strongly recommend procedure to their friends, irrespective of endoscopist. Multivariate regression analysis showed that women were more likely to have significant pain or discomfort than men (P ! .001). Conclusions: This study has shown that there are no significant differences in patient satisfaction with lower gastrointestinal endoscopy performed by a nurse, doctor or non-medical colonoscopists.