CiteSpace software was used to conduct scientometric analysis on the research and intervention measures of geriatric depression (GD) at home and abroad, revealing the research hotspots, evolution process and development trend of Chinese and Western medicine. It was found that the United States remains absolutely dominant, regardless of the breadth of the research area, the number of publications, or the influence. Western medicine has focused its recent research on mortality in a number of domains, including instrumental activity, cognitive assessment, international society, and treatment response. Chinese medicine, on the other hand, focuses on investigating the pathophysiology and holistic treatments of depression in older adults. Traditional Chinese medicine (TCM) treatment of geriatric depression exhibits the qualities of minimal toxicity and side effects, minimal or no trauma, and evident clinical results. As a global public health problem, the active promotion of inter-country cooperation and joint interdisciplinary interventions is the development trend.