Presently known strained cycloalkynes with one, two or three additional cis- or trans-configurated double bonds are summarized in Table 3. The main topics of this article are the geometrical ring strain, the preparation or in situ generation of these compounds by fragmentation of the corresponding 1,2,3-selenadiazoles, and the thermal isomerization processes performed at room temperature or in flash pyrolysis experiments at 440–640°.