In the past two decades, the computer technology industry has developed rapidly, and the geological prospecting industry is also undergoing a computerized and electronic revolution. The application technology of new geological information systems is gradually adding us to the spatial information system of geological prospecting projects. In order to deeply study the current situation of the artificial neural network model in the spatial analysis of our country’s geographic information system, this paper uses the traditional classification analysis method; database analysis and neural network analysis method of compensating samples were collected, an artificial model of the network is established, and the algorithm is simplified. And a neural network model is created. In the research of A and B counties’ geographic information system, using a new network model, 61 geological disasters were found in County A, of which 47 were landslides, 4 collapses, and 10 unstable slopes. There were 19 geographical disasters in County B, including 9 unstable slopes, 6 landslides and 4 collapses. In terms of geographic prediction combined with the network model, the comparison with the actual situation shows that the geographical distribution is 99.7% in the geographical and geological disaster-prone areas, and the geographical distribution is less in the nonprone areas, with a proportion of 0.3%. Geological disaster-prone areas of low points accounted for 76.9%, and the number of disaster-affected points in the low-prone areas accounted for 22.8%. The geographical and geological grades divided by the evaluation model are basically consistent with the actual grades, which can meet the needs of geographic evaluation. It is basically realized that starting from the model’s geographic information system, a more comprehensive and practical artificial neural network model is designed.