Merauke Regency is one of the districts in the South Papua Province, geographically located between 1370 - 1410 East Longitude and 50 - 90 South Latitude. With an area of up to 45,013.35 km2 or 38.2 percent of the total area of South Papua Province, making Merauke Regency the largest district not only in South Papua Province but also among other districts in Indonesia. Administratively, Merauke Regency has 22 districts. With the expansion of new provincial territories, Merauke Regency became part of South Papua Province along with Boven Digoel, Asmat and Mappi Regencies. This expansion is based on Law No. 14 of 2022. Merauke has 22 districts/sub-districts and 190 villages. The existence of 190 villages means that spatial data collection is still considered a normal thing, even though spatial data collection in an area is very important, especially with current technological advances. Accurate and integrated management of spatial data is important in planning and decision making in a region, especially in the Nasai Village area, South Papua. This research aims to examine a comprehensive spatial data handling system in this area, using Geographic Information System (GIS) technology as a tool. The methods used in this research include identifying needs and problems related to spatial data, collecting spatial and non-spatial data, as well as designing an integrated geographic information system. It is hoped that the results of this research will provide an overview of the current condition of spatial data management in Nasai Village and provide system recommendations that can increase the efficiency and effectiveness of geographic information management in the area.