In this paper, we introduce a new class of (p, q)-analogue type of Fubini numbers and polynomials and investigate some properties of these polynomials. We establish summation formulas of these polynomials by summation techniques series. Furthermore, we consider some relationships for (p, q)-Fubini polynomials associated with (p, q)-Bernoulli polynomials, (p, q)-Euler polynomials and (p, q)-Genocchi polynomials and (p, q)-Stirling numbers of the second kind.