You have accessJournal of UrologyTrauma/Reconstruction/Diversion: Ureter (including Pyeloplasty) and Bladder Reconstruction (including fistula), Augmentation, Substitution, Diversion I1 Apr 2018MP49-11 DOES RADIATION EXPOSURE PORTEND WORSE POSTOPERATIVE OUTCOMES AFTER CYSTECTOMY WITH URINARY DIVERSION FOR BENIGN INDICATIONS? Paurush Babbar, Andrew Sun, Ann Kim, Daniel Hettel, Shree Agrawal, Alice Crane, Daniel Sun, Ryan Berglund, Hadley Wood, and Kenneth Angermeier Paurush BabbarPaurush Babbar More articles by this author , Andrew SunAndrew Sun More articles by this author , Ann KimAnn Kim More articles by this author , Daniel HettelDaniel Hettel More articles by this author , Shree AgrawalShree Agrawal More articles by this author , Alice CraneAlice Crane More articles by this author , Daniel SunDaniel Sun More articles by this author , Ryan BerglundRyan Berglund More articles by this author , Hadley WoodHadley Wood More articles by this author , and Kenneth AngermeierKenneth Angermeier More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.1602AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Preoperative radiation exposure is traditionally thought to correlate with increased postoperative complications after cystectomy with urinary diversion (CxUD) for benign indications. We assessed postoperative outcomes among patients who received CxUD, stratified by radiation exposure. METHODS A retrospective review of patients undergoing CxUD over a 10 year period encompassed demographics, operative parameters, 30 and 90 day readmission and complications. CxUD for malignant indications and in patients below 18 years of age were excluded. Chi-square and t-test analyses assessed demographics and indications. Complications were measured by univariate and multivariate logistic regression models. RESULTS Among 103 patients, 39 (38%) had radiation exposure prior to CxUD. Mean age for patients with radiation exposure undergoing cystectomy and urinary diversion was significantly higher (69.8 vs 59.7 years, p=0.001). In patients receiving preoperative radiation, 23.1% (9/39) had congestive heart failure (p=0.005). Other preexisting conditions such as diabetes, previous myocardial infarction, renal disease and liver disease were not associated with radiation exposure. Operative time (p=0.861), estimated blood loss (p=0.756) and length of stay (p=0.776) were not associated with radiation exposure. There was a significant correlation between radiation exposure and having a preoperative diagnosis of genitourinary fistulae (p=0.001), neurogenic bladder (p<0.0001) and urethral stricture (p=0.002). Radiation exposure did not correlate to readmission at 30 days (p=0.256) or at 90 days (p=0.576). Ureteroileal strictures requiring interventional radiology procedures were observed in 6 patients (5.8%) and stomal stenosis was seen in 2 patients (1.9%). Neither variable was correlated with radiation exposure (p=0.27 and p=0.265, respectively). CONCLUSIONS In spite of patients being older with more comorbidities at baseline, patients with preoperative radiation exposure undergoing CxUD for benign indications did not have increased readmission at 30 or 90 days or increased complications postoperatively. Additionally, operative parameters such as surgery time, estimated blood loss and length of stay were similar between radiation and naïve patient groups. These findings suggest radiation exposure prior to CxUD may not portend as negative consequences as once thought. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e670 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Paurush Babbar More articles by this author Andrew Sun More articles by this author Ann Kim More articles by this author Daniel Hettel More articles by this author Shree Agrawal More articles by this author Alice Crane More articles by this author Daniel Sun More articles by this author Ryan Berglund More articles by this author Hadley Wood More articles by this author Kenneth Angermeier More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...