Kitchen anaerobic wastewater contains a high concentration of insoluble organic matter, and the degradation of organic matter in the wastewater is the key to treating kitchen anaerobic wastewater. The Fenton oxidation process is used to treat kitchen anaerobic wastewater, and the effects of H2O2 dosage, Fe2+ dosage, reaction time and pH value on chemical oxygen demand (COD) degradation efficiency are explored. The improved particle swarm optimization (IPSO) algorithm is used to optimize the back propagation (BP) neural network, and a prediction model of COD degradation is established based on IPSO‐BP neural network. H2O2 dosage, Fe2+ dosage, reaction time and pH value are selected as the main influencing factors of the COD degradation, and 30 groups of experimental data are selected to train the IPSO‐BP neural network. The results predicted by the trained IPSO‐BP neural network on 10 groups of test data are compared with the actual values, and the results predicted by BP model and genetic algorithm‐BP (GA‐BP) model are compared. The IPSO‐BP model has the highest fitting accuracy. The root mean square error (RMSE), RMSE coefficient of variation (CV‐RMSE), and coefficient of determination (R2) were used to evaluate the prediction performance of the model. The indicators of the IPSO‐BP model were significantly better than those of the GA‐BP model and the BP model, indicating that IPSO‐BP model had better generalization ability and could predict COD concentration more effectively. The optimal conditions for Fenton oxidation obtained from IPSO‐BP model are as follows: the dosage of H2O2 is 2000 mg/L, the dosage of Fe2+ is 1200 mg/L, the pH value is 2.8, the reaction time is 75 min, and the COD removal rate is 80.125%, which is consistent with the experimental results. Through gas chromatography‐mass spectrometry (GC‐MS) analysis, most organic compounds in kitchen anaerobic wastewater are oxidized and decomposed, indicating that the IPSO‐BP model has good predictive quality.
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