General Well-being Scores Research Articles

No more government-imposed societal-level COVID-19 control measures but still significant self-experienced burden for severely immunocompromised individuals – A cross-sectional survey in the Netherlands

ObjectivesIn March 2023, all societal-level COVID-19 control measures were lifted by the Dutch government. This study was performed to understand the self-experienced burden of this new phase of COVID-19 on the perspectives and behaviors of severely immunocompromised individuals. MethodsThis is an observational, descriptive, cross-sectional study in The Netherlands. An online survey was completed by severely immunocompromised individuals, to capture their general well-being (score from 1 = worst to 10 = best), mental and physical health, and daily and social activities during survey conduct and retrospectively for before onset of COVID-19. The survey was open for completion from May 24th until August 7nd, 2023. ResultsOf the 236 respondents, 96.6 % had been vaccinated against COVID-19 and 24.6 % were shielding to avoid COVID-19 during survey conduct. The general well-being score for all respondents was 7.5 (±1.2 SD) before onset of the COVID-19 pandemic and 6.9 (±1.6 SD) during survey conduct (P<0.001). For the shielding group (n = 58), these scores were 7.6 (±1.0 SD) and 5.7 (±1.6 SD), respectively (P<0.001). Generally, for all questions about mental and physical health and daily and social activities, there was a trend towards more negative answers during survey conduct, compared with before onset of the COVID-19 pandemic, which was more pronounced for the shielding group. ConclusionsDespite absence of government-imposed societal measures, COVID-19 avoidance still had a self-experienced burden on perspectives and behaviors of immunocompromised individuals in The Netherlands, with a significantly lower general well-being during survey conduct, compared with before onset of COVID-19.

Anorectal malformation and Hirschsprung’s disease: a cross-sectional multicentre comparison of quality of life and bowel function to a healthy population

PurposeChildren with anorectal malformation (ARM) and Hirschsprung’s disease (HD) often experience bowel symptoms into adulthood, despite definitive surgery. This study evaluates the quality of life (QOL) and bowel functional outcome...

Analysis of the correlation between general postpartum well-being and depression in primiparas: A cross-sectional study.

To investigate the status quo and influencing factors of general postpartum well-being in primiparas, analyze its correlation with postpartum depression, and provide a theoretical foundation for enhancing the postpartum well-being of primiparas. From the start of November 2021 to the end of December 2021, the General Information Questionnaire, General Well-Being Scale, and the Edinburgh Postpartum Depression Scale were used to survey primiparas in a tertiary hospital, and the correlation between general well-being and postpartum depression was analyzed. We surveyed a total of 225 primiparas. The average score for general well-being in primiparas was 77.84 ± 6.83, and the total score for postpartum depression was 9.11 ± 2.51. Confinement location, planned pregnancy, pregnancy complications, neonatal sex, medical expenses, etc, had statistically significant effects on the general well-being scores (P < .05), whereas per capita monthly income, pregnancy complications, maternal and infant care skills, and medical expenses had statistically significant effects on postpartum depression scores (P < .05). Postpartum depression scores were negatively correlated with general well-being, health anxiety, energy, sad or happy mood, relaxation, and tension. There is a negative correlation between the general well-being of primiparas and postpartum depression, suggesting that in clinical care, the focus should be on primiparas with pregnancy complications, and psychological counseling should be provided in advance to prevent postpartum depression and the resulting decrease in well-being.

The effect of a fatigue self-management program based on individual and family self-management theory in cancer patients: A single-blinded randomized controlled trial

PurposeThis study was conducted to investigate the effect of the Fatigue Self-Management Program based on the Individual and Family Self-Management Theory on fatigue, daily living activities, and well-being in cancer patients. MethodsThis randomized controlled single-blind experimental study was carried out between November 2020 and April 2022. A total of 94 patients with advanced cancer, 47 in each group, were included in the study, and 57 participants completed the study. Data were collected using the Brief Fatigue Inventory, Katz Index of Independence in Activities of Daily Living, and Well-Being Questionnaire-22. The Fatigue Self-Management Program based on Individual and Family Self-Management Theory was delivered to the intervention group with two face-to-face and two tele-monitoring sessions. No intervention was applied to the control group, who received only routine care. ResultsThe mean score of fatigue in the intervention group compared to the control group decreased, and the difference was statistically significant (p < .05); daily living activities mean scores were higher than the control group, but there was no statistically significant difference (p > .05). The mean scores of depression and anxiety in the intervention group were lower than those in the control group; energy, positive well-being, and general well-being mean scores were found to be higher than those in the control group, and the difference was statistically significant (p < .05). ConclusionsThe Fatigue Self-Management Program effectively reduces the fatigue experienced by cancer patients and increases their well-being but it does not increase their independence in daily living activities. Clinical trial registryNCT04822220

OGBN O03 Quality of life of patients with gastroesophageal reflux disease: findings from a systematic literature review

Abstract Background Gastroesophageal reflux disease (GERD), affecting over a billion people worldwide, is associated with significant impairment and productivity loss. Understanding the quality of life among GERD patients may provide important clinical relevance to treatment management and highlight the patient perspective. The aim of this study was to conduct a systematic review of GERD and quality of life, including any potential effects on treatment management. Methods MEDLINE, Embase, and the Cochrane Library were searched for randomized controlled trials, case-control, and cohort studies published in English from 2013 to 2023. Eligible studies included adult GERD patients with quality of life data from a disease-specific or generic instrument. Data analysis contained a narrative synthesis of pre- and post-procedural total scores. Results Eight trials and 34 observational studies were included. The disease-specific instruments GERD Health-Related Quality of Life (GERD-HRQL) (n = 35) and Gastrointestinal Quality of Life Index (GIQLI) (n = 4) had baseline mean scores ranging from 13.3 to 37.1 and 72.0 to 96.3, which changed to 1.3 to 31.6 and 94.8 to 119.8 post-treatment, respectively. Besides the Reflux Symptom Index (RSI) (n = 3), EQ-5D, Psychological General Well-Being (PGWB), SF-36, and GastroEsophageal Reflux Symptom Score (GERSS) were only used by single studies to evaluate the quality of life among GERD patients. In general, these results indicated an improvement post-treatment. Conclusions As a general finding, patients with GERD have poor quality of life and active treatment seems to influence and improve GERD patients’ quality of life, considering the pre-post results of GERD-HRQL and GIQLI scores. As expected, generic quality of life instruments are seldom used.

A Positive-Psychology-based Multiple Regression model predicting Wellbeing in Chilean Youth

Positive Youth Development (PYD) addresses young people from their potential, strengths, and assets, in contrast to the deficit view that focuses on their weaknesses. The PYD model promotes constructive behaviours in youth by underscoring positive attributes usually found during the transition from childhood to adulthood in order to foster healthy development. In a nutshell, PYD comprises five key competence (5C), forty developmental assets, and the flourishing model. In the present study, 261 participants were approached by an online survey (nWomen= 189, nMen = 72, MeanAge= 22 years old), as part of the Cross-national project on PYD (CN-PYD), which included several measures, among which those included in the research were: The Developmental assets Scale, the Short-form of the Five Cs, and the Mental Health Continuum Short-Form (MHC-SF). Emotional, Social, Psychological and General Wellbeing scores were tested on the premise that females would score significantly lower than male participants (H1). In addition, two multiple regression models were tested with the first wave of the Chilean PYD project on the premise that Positive Identity, Confidence, Character, and Connection would predict the variance of General Wellbeing (H2), and Psychological Wellbeing (H3). The findings provided total support for H1 and H2, and partial support for H3. Overall, the research complements previous investigations conducted with Latin American and Chilean Youth, stressing the importance of researching Latin-American adolescents’ developmental assets, PYD competence, and the varieties of subjective wellbeing.

Effectiveness of a Teaching Kitchen Intervention on Dietary Intake, Cooking Self-Efficacy, and Psychosocial Health

ABSTRACT Background The consumption of fruits, vegetables, and whole grains (FVWG) has been associated with decreased risk of chronic disease, yet over 80% of U.S. adults do not meet dietary recommendations for FVWG. Purpose This study explored the effectiveness of a teaching kitchen intervention upon consumption of FVWG and overall dietary patterns. Cooking self-efficacy, comfort in the kitchen, and elements of psychosocial health were also assessed. Methods Participants were recruited to the 5-week Complete Health Improvement Program–Teaching Kitchen (CHIP-TK) through a worksite wellness initiative. The program, based upon elements of the social cognitive theory, included cooking classes, health education, and horticulture activities. Pre- and post-surveys were administered and evaluated. Results CHIP-TK led to significant increases in FVWG intake. Cooking self-efficacy, comfort in the kitchen, and general well-being scores also improved, with medium-to-large effect sizes. Participant feedback indicated weekly meetings, hands-on cooking classes, facilitator expertise, and group camaraderie were keys to success in the program. Discussion Teaching kitchens are well-received within a worksite setting and have the potential to improve dietary intake patterns and psychosocial health.Translation to Health Education Practice: Health educators should design and implement integrative, theory-driven programs to improve nutritional status, well-being, and overall health.

CT-039 Health-Related Quality of Life Following Allogeneic Hematopoietic Stem Cell Transplantation With Omidubicel Versus Standard Umbilical Cord Blood

Omidubicel is an ex vivo expanded stem cell product derived from umbilical cord blood (UCB) for allogeneic hematopoietic stem cell transplantation (allo-HSCT). A multicenter phase III trial demonstrated faster engraftment and fewer infections with omidubicel versus standard UCB. To compare patient-reported health-related quality of life (HRQL) between omidubicel and UCB. Patients with hematologic malignancies undergoing allo-HSCT were randomized 1:1 to omidubicel or UCB between 2017-2020. Validated HRQL surveys (FACT-BMT and EQ-5D-3L) were administered on screening and days 42, 100, 180, and 365 post-transplant. Twenty-eight international academic centers. Among 108 patients undergoing allo-HSCT, 75 (69%) who completed HRQL surveys at screening and on at least one follow-up visit were included. Baseline characteristics were similar between arms, with a mean age of 36, 59% male, 41% non-white, and 77% intermediate/high disease risk. Most common diagnoses were AML (45%) and ALL (35%). Myeloablative allo-HSCT with omidubicel or UCB followed by standard GVHD prophylaxis with a calcineurin inhibitor and mycophenolate mofetil. This is a secondary exploratory analysis evaluating changes in FACT-BMT and EQ-5D-3L post-transplant, measuring physical, functional, emotional, family/social, and overall well-being. HRQL scores over the first 365 days were compared using the area under the curve (AUC) of mean HRQL trajectories in each arm. Baseline HRQL scores were similar between the two arms. Initial HRQL declines at day 42 were numerically better with omidubicel. Over the first year, AUC of physical well-being scores was better with omidubicel (p = 0.02, mean difference 1.5-3.1), exceeding the minimal clinically important difference (MCID) of 2 points on days 180 and 365. Similarly, AUCs of HSCT-specific and functional well-being scores favored omidubicel (p = 0.04). AUCs of total FACT-BMT scores were better with omidubicel (p = 0.01, mean difference 7.2-11), exceeding the MCID of 7 points at all time points. There were numerical but non-significant improvements in AUCs of FACT-BMT social/family, emotional, and EQ-5D-3L general well-being scores with omidubicel. Omidubicel showed clinically meaningful and sustained improvements in physical, functional, and overall well-being compared to UCB transplantation.

Quality of Life and General Well-being in People Receiving Hemodialysis Treatment: A Cross-sectional Study

Background: End-stage renal disease and hemodialysis treatment are debilitating and progressive and can significantly impact patients’ general well-being and quality of life. Understanding the impact of end-stage renal disease and hemodialysis on Jordanian patients may help healthcare providers improve the type of care delivered. Purpose: This study aimed to examine the quality of life and general well-being of patients undergoing hemodialysis treatment and to examine the differences in quality of life and general well-being scores based on participant age and gender. Methods: This was a cross-sectional study in which 203 patients were recruited from different dialysis units across Jordan. Valid questionnaires were used to collect data on quality of life and general well-being, along with a demographic data sheet. Results: Participants scored moderately low on general well-being, with the highest mean for the social dysfunction and the depression sub-scales, respectively. The highest reported score was on the social relationships domain of quality of life, while the lowest was for the physical domain. Age groups significantly differed in their scores of general well-being and all domains of quality of life apart from the environmental domain. Female participants had significantly higher (worse) scores than males in terms of the total scores on general well-being and on somatic symptoms and depression sub-scales of general well-being. Conclusion: It was shown that hemodialysis treatment negatively influences patients’ quality of life and general well-being and interferes with their day-to-day lives. Implications for Nursing: Dialysis nurses play a vital role in monitoring and supporting their patients and might provide an avenue by which they can optimize patients’ quality of life and general well-being. Hence, working with patients to find the best possible care plan may positively impact patients’ lives and health outcomes. Keywords: Cross-sectional study, Hemodialysis, Quality of life, General well-being.

Second-Generation Antipsychotics' Effectiveness and Tolerability: A Review of Real-World Studies in Patients with Schizophrenia and Related Disorders.

Despite methodological limitations, real-world studies might support clinicians by broadening the knowledge of antipsychotics’ (APs) effectiveness and tolerability in different clinical scenarios and complement clinical trials. We conducted an extensive literature search in the PubMed database to evaluate the effectiveness and tolerability profiles of second-generation antipsychotics (SGAs) from real-world studies to aid clinicians and researchers in selecting the proper treatment for patients with schizophrenia and related disorders. The present review evidenced that SGAs demonstrated superior effectiveness over first-generation antipsychotics (FGAs) in relapse-free survival and psychiatric hospitalization rate and for treating negative symptoms. Persistence and adherence to therapy were higher in SGAs than FGAs. Most studies concluded that switching to long-acting injectables (LAIs) was significantly associated with a lower treatment failure rate than monotherapy with oral SGAs. Considerable improvements in general functionality, subjective well-being, and total score on global satisfaction tests, besides improved personal and social performance, were reported in some studies on patients treated with LAI SGAs. Clozapine was also associated with the lowest rates of treatment failure and greater effectiveness over the other SGAs, although with more severe side effects. Effectiveness on primary negative symptoms and cognitive deficits was rarely measured in these studies. Based on the data analyzed in the present review, new treatments are needed with better tolerability and improved effectiveness for negative, affective, and cognitive symptoms.

Burden and Correlates of Mental Health Symptoms Among Young Black Gay, Bisexual, and Other Men Who Have Sex with Men Engaged in HIV Care in Atlanta.

Mental health comorbidities are prevalent among young Black gay, bisexual, and other men who have sex with men (YB-GBMSM) living with HIV and can adversely impact HIV-related outcomes. We conducted a cross-sectional survey study with 100 YB-GBMSM recruited from two HIV care centers in Atlanta, and constructed multivariable logistic and linear regression models to examine correlates of depression, anxiety, trauma symptoms, and general well-being. In adjusted models, full-time employment was associated with fewer depressive symptoms, while HIV stigma and substance use were associated with higher levels of depressive symptoms. Younger age and full-time employment were negatively associated with severe anxiety, while HIV stigma was positively associated with severe anxiety and trauma symptoms. Trust in physicians, lower HIV stigma, full-time employment, and lack of substance use were associated with higher average general well-being scores. In conclusion, we found high frequency of depressive, anxiety, and trauma-related symptoms among this sample of YB-GBMSM living with HIV. Unemployment, substance use, and HIV stigma emerged as particularly salient correlates of psychological morbidity, suggesting a need for structural and community-level interventions to address mental health in this population.

Impact of Infectious Disease after Lactococcus lactis Strain Plasma Intake in Vietnamese Schoolchildren: A Randomized, Placebo-Controlled, Double-Blind Study.

Lactococcus lactis strain Plasma (LC-Plasma) is reported to have anti-viral effects via direct activation of plasmacytoid dendritic cells, which upregulate the production of type I and III interferons. A randomized, placebo-controlled, double-blind, parallel group study was designed for elementary schoolchildren, grades 1 to 3, in Vietnam. LC-Plasma or a control were administered to schoolchildren as a beverage (1.0 × 1011 count LC-Plasma/day/person). The primary endpoint was to determine the efficacy of LC-Plasma in reducing the cumulative days absent from school due to upper respiratory disease (URID) and gastrointestinal disease (GID), and the secondary endpoint was to evaluate the potency of LC-Plasma on URID/GID symptoms and general well-being scores. LC-Plasma intake significantly reduced the cumulative days absent from school due to URID/GID (Odds ratio (OR) = 0.57, p = 0.004) and URID alone (OR = 0.56, p = 0.005); LC-Plasma also significantly reduced the number of cumulative fever positive days during the first 4 weeks of intervention (OR = 0.58, p = 0.001) and cumulative days with diarrhea during the last 4 weeks of the intervention period (OR = 0.78, p = 0.01). The number of positive general wellbeing days was significantly improved in the LC-Plasma group compared with the control throughout the intervention period (OR = 0.93, 0.93, p = 0.03, 0.04 in the first and last 4 weeks of the intervention, respectively). These data suggest that LC-Plasma seems to improve the health condition of elementary schoolchildren and reduces school absenteeism due to infectious disease, especially URID.

Impact of COVID 19 on General Wellbeing of Working Women in Kerala

Health is a state of complete physical, mental, social and spiritual well-being not merely the absence ofdisease or infirmity (WHO) and it is multi factorial.Women’s health is at a crossroads. Methods:A descriptivestudy with a quantitative approach was conducted n August – September 2020. The sample consisted of100 working women selected by snowball sampling technique. Data were collected using modified generalwellbeing scale which was prepared and administered online by the investigators. Results:The meanpercentage of the general wellbeing score was 73.8.The findings of the study show that only 3% of thewomen had very good and 79% of them had good general wellbeing. It also depicts that 17% of them hadaverage and only 1% had poor general wellbeing.Discussion: Today, women’s roles are emerging differentlywith new commitment and career oriented as well as commitment to families. In the present scenario,women at work can be seen everywhere whether in or outside India. Working women also play multipleroles such as child rearers, parents, teachers, caretakers of their elderly parents, and many more, whichbecome very much strenuous for them. It is the added responsibility and burden of chores that add to dailyhassles or stress for them, especially in working women with young children, which definitely affect theirpsychological well-being3.

Patient-Reported Outcome Measures in Colorectal Surgery: Construction of Core Measures Using Open-Source Research Method.

Purpose. The primary aim of the study was to review the existing literature about patient-reported outcome measures (PROMs) in colorectal cancer and IBD. The secondary aim was to present a road map to develop a core outcome set via opinion gathering using social media. Method. This study is the first step of a three-step project aimed at constructing simple, applicable PROMs in colorectal surgery. This article was written in a collaborative manner with authors invited both through Twitter via the #OpenSourceResearch hashtag. The 5 most used PROMs were presented and discussed as slides/images on Twitter. Inputs from a wide spectrum of participants including researchers, surgeons, physicians, nurses, patients, and patients' organizations were collected and analyzed. The final draft was emailed to all contributors and 6 patients' representatives for proofreading and approval. Results. Five PROM sets were identified and discussed: EORTC QLQ-CR29, IBDQ short health questionnaire, EORTC QLQ-C30, ED-Q5-5L, and Short Form-36. There were 315 tweets posted by 50 tweeters with 1458 retweets. Awareness about PROMs was generally limited. The general psycho-physical well-being score (GPP) was suggested and discussed, and then a survey was conducted in which more than 2/3 of voters agreed that GPP covers the most important aspects in PROMs. Conclusion. Despite the limitations of this exploratory study, it offered a new method to conduct clinical research with opportunity to engage patients. The general psycho-physical well-being score suggested as simple, applicable PROMs to be eventually combined procedure-specific, disease-specific, or symptom-specific PROMs if needed.

Determination of Quality of Life and Self-Care Agency in Patients Who Underwent Colorectal Cancer Surgery: A Prospective Descriptive Study

Knowledge about the relationship between quality of life and self-care among patients with colorectal cancer in Turkey is limited. This prospective, descriptive study evaluated the quality of life and self-care agency of patients who underwent surgery for colorectal cancer. Patients were recruited to participate preoperatively from the general surgery clinics in 2 hospitals in Turkey. Sociodemographic variables were collected preoperatively, and the Quality of Life Scale for Cancer Patients (EORTC QLQ-C30) Turkish Version 3.0, the Quality of Life Scale for Colorectal Cancer Patients (EORTC QLQ-CR29), and the Self-Care Agency Scale were completed preoperatively and at 1, 3, and 6 months postoperatively. Thirty-seven (37) patients (average age 59.49 years [±10.84]) who met the inclusion criteria participated in the study. The majority were male (22 patients; 60%), and 25 (67%) did not have a stoma postoperatively. Compared with preoperative scores, QLQ-C30 general well-being, functional status, physical functions, and role performance scores decreased in the first month after surgery and increased in the third and sixth months (58.3 [preoperative] vs 75.0 [month 3] vs 83.3 [month 6]; P = .000). The preoperative QLQ-CR29 excretory system pleasure scores were higher than the postoperative third- and sixth-month scores (1.7 [preoperative] vs 1.0 [month 3] vs 1.0 [month 6]; P = .001). The Self-Care Agency scores at 6 months were higher than the postoperative first month (109.62 ± 11.62 vs 115.19 ± 14.22; P = .006). A positive correlation was found between Self-Care Agency scores and functional status scores of the QLQ-C30 scale at 3 and 6 months postoperatively (P = .000). Quality of life and Self-Care Agency scores decreased immediately after surgery but increased in the following 6 months. A positive correlation was found between quality of life and self-care agency.

Preoperative communication with anesthetists via anesthesia service platform (ASP) helps alleviate patients\u2019 preoperative anxiety

Female gender has been identified as one of the risk factors closely linked to perioperative anxiety and a lower level of satisfaction. A successful preoperative anesthesia education may improve such negative outcomes. The aim of this study was to investigate whether preoperative anesthesia education via an Anesthesia Service Platform (ASP) could reduce the anxiety levels in female patients scheduled for laparoscopic cholecystectomy under general anesthesia, and accelerate rehabilitation. A total of 222 patients scheduled for elective laparoscopic cholecystectomy were randomly assigned to the control group and the ASP group. Patients’ baseline and post-intervention psychological status was measured by the State-Trait Anxiety Inventory and General Well-Being Schedule. Pain management and recovery were assessed by VAS every 12 h for 48 h after surgery; length of stay (LOS) and postoperative analgesic consumption were also assessed. Patients in the control group experienced higher anxiety levels before surgery and had longer LOS than those in the ASP group. Patients in the ASP group had a higher general well-being score; however, they suffered more pain and consumed more analgesics after surgery. ASP is effective for preventing anxiety in female patients before laparoscopic cholecystectomy, improving patients’ general well-being levels, and shortening their LOS, but negatively influences patients’ postoperative pain levels.

Self-efficacy, recovery and psychological wellbeing one to five years after heart transplantation: a Swedish cross-sectional study.

Self-efficacy refers to a person´s confidence in carrying out treatment-related activities and constitutes the foundation of self-management as well as long-term follow-up after heart transplantation. Exploring the heart recipients´ experiences by means of self-report instruments provides healthcare professionals with valuable information on how to supply self-management support after heart transplantation. The aim was to explore self-efficacy in relation to the self-reported level of recovery and psychological wellbeing, among adult heart recipients, one to 5 years after transplantation. This cross-sectional study includes 79 heart recipients, due for follow-up one to 5 years after transplantation. Three different self-assessment instruments were employed: the self-efficacy for managing chronic disease 6-item scale; the postoperative recovery profile; and the psychological general wellbeing instrument. The reported level of self-efficacy was high (median 8.3, maximum score 10). Significantly higher self-efficacy was seen among those who had returned to work (P = 0.003) and those without pre-transplant mechanical circulatory support (P = 0.033). In total, 65.5% (n = 52) reported being reasonably recovered, while 18.8% (n = 12) were not recovered. The median total psychological general wellbeing score was 108 (P25 = 24, P75 = 117), suggesting overall good psychological wellbeing in the whole group of heart recipients. The heart transplant recipients in our study had an overall high level of self-efficacy. Low self-efficacy was found among those with a low self-reported level of recovery, pre-transplant treatment with mechanical circulatory support or who had not returned to work. This is important information for transplant professionals when helping heart recipients to balance their expectations about recovery.

Effect of radiotherapy for rectal cancer on female sexual function: a prospective cohort study.

Abstract Background Clinical experience and limited data show that female sexual function is influenced negatively by preoperative radiotherapy (RT) for rectal cancer. The aim of this prospective study was to investigate the impact of RT on sexual function and ovarian reserve measured by levels of anti-Müllerian hormone (AMH). Methods Women with stage I–III rectal cancer scheduled for surgery with or without preoperative (chemo)RT were included and followed for 2 years. Female Sexual Function Index (FSFI) questionnaire responses and blood samples for hormone analyses, including AMH in women aged 45 years or less, were collected at baseline and during follow-up. Results In the group of 109 women who received preoperative RT, median scores in all FSFI domains decreased over time, as did the total FSFI score (from 18·5 (range 2·0–36·0) at baseline to 10·8 (2·0–34·8) at 2 years; P &amp;lt; 0·001). In the group of 30 women who did not receive preoperative RT, only satisfaction declined over time (from 3·2 (0·8–6·0) to 1·8 (0·8–6·0); P = 0·012). In longitudinal regression analysis, the mean decline in FSFI total score was –9·33 (95 per cent c.i. –16·66 to –1·99; P = 0·013) for women who had preoperative RT compared with those who did not, with adjustment for age, Psychological General Well-being Index score and relationship with partner. A corresponding association was seen for arousal, lubrication, orgasm and pain. Five of six women aged 45 years or less with detectable serum levels of AMH at baseline had undetectable levels after RT. Conclusion Preoperative RT was associated with impairment in sexual function in women with rectal cancer. This needs to be considered when discussing choice of treatment and rehabilitation. In younger women, undetectable AMH levels after RT indicate an irreversible loss of ovarian follicles.

Psychological well-being of adolescents gifted in math, humanities and sports: Comparative analysis

Psychological well-being is an important factor for the successful realisation of gifted adolescents’ potential, and therefore research in this subject area has not only theoretical, but also practical significance. The results of contemporary research on gifted adolescents’ well-being are contradictory, and several decades of discussions about the relationship between giftedness and psychological well-being have yielded no consensus. This ambiguity may arguably be explained by the gifted adolescents’ activity type and gender. In this article, a study of the psychological well-being of adolescents (n = 168, age 15–17) gifted in math, humanities and sports who are enrolled in advanced programmes for gifted children is presented. The eudemonic concept of psychological well-being developed by Carol Ryff served as the theoretical framework of the study. Respondents’ psychological well-being was measured using Ryff’s Psychological Well-Being Scales as adapted into Russian by L. V. Zhukovskaya and E. G. Troshikhina. The study aimed to identify and analyse possible differences in the psychological well-being of gifted teenagers depending on their gender and type of giftedness. The results suggest that while the respondents’ general well-being score is not determined by their type of giftedness or gender, specific factors of psychological well-being, such as purpose in life and self-acceptance, do correlate with giftedness type. The highest scores were found in the sample of adolescents who are gifted in humanities. All detected gender differences fall under age-specific trends of personal development in adolescence, and giftedness type might reinforce these trends. The results of current study contribute to better understanding of the relationship between psychological well-being and giftedness in adolescence.

Assessment of long-term yoga training as a complementary therapeutic measure for anxiety, depression, and psychological distress in healthy individuals

Background: Sustained increase in disturbed psychological health is a global concern at present. Complementary therapies in addition to pharmacological interventions are frequently advised to prevent consequential systemic and psychological disorders. However, data pertaining to long-term yoga practice as a complementary therapeutic intervention in healthy adults with large sample size are least available, indicating the significant gap in the scientific literature. Aims and Objectives: The present study aims to assess the usefulness of yoga as complementary measure for anxiety, depression, and psychological distress in healthy individuals. Materials and Methods: The pre- and post-interventional yoga interventional study was conducted on healthy individuals (n = 200) with age ranging from 30 to 50 years (mean age = 39.95 years). Yoga intervention was given for 6 months (1 h/day; 6 days/week). Baseline and post-interventional anxiety, depression, life satisfaction, loss of emotional control, general positive affect, emotional ties, psychological distress, and well-being scores were measured using a questionnaire-based mental health inventory-38. The data were collected in SPSS and analyzed using paired t-test. Significance was established at 5% P-value. Results: An intervention of yoga for 6 months caused highly significant (P < 0.0001) reduction in anxiety, depression, and psychological distress scores and improvement in the loss of emotional control, general positive affect, life satisfaction, and psychological well-being scores. Conclusion: Positive results indicate the usefulness of long-term yogic exercise modality as a complementary therapeutic intervention for anxiety, depression, and psychological distress in healthy individuals.