Review Objective: The main objective of the review is to evaluate the effectiveness of physiotherapy care compared to general practitioner care in outcomes (i.e. pain experienced, function and economic cost) for adults with acute LBP. Review Questions: The specific review questions are: • Is general practitioner care (prescription of non-steroidal anti-inflammatory drugs, analgesics, muscle relaxants, bed rest and advice) more effective in decreasing pain compared to physiotherapy care (mobilization/manipulation, education and exercise therapy) in the management of adults with acute LBP? • Is general practitioner care (prescription of non-steroidal anti-inflammatory drugs, analgesics, muscle relaxants, bed rest and advice) more effective at improving function compared with physiotherapy care (mobilization/manipulation, education and exercise therapy) in the management of adults with acute LBP? • Is general practitioner care (prescription of non-steroidal anti-inflammatory drugs, analgesics, muscle relaxants, bed rest and advice) more economically cost effective compared with physiotherapy care (mobilization/ manipulation, education and exercise therapy) in the management of adults with acute LBP Criteria for considering studies for this review: Type of participants: This review will consider studies that examine male and female participants over the age of eighteen years of age with non-specific acute low back pain. Studies that include subjects presenting with low back pain recognized as a specific pathology such as pain due to nerve root involvement or serious spinal pathology including skeletal infections, tumors, osteoporosis, ankylosing spondylitis, fractures, inflammatory process, nerve root involvement or cauda equina syndrome, will be excluded. Types of interventions: The interventions most commonly administered by a physiotherapist in the management of acute LBP will include mobilizations/manipulations, exercises and education9. Types of Comparison: The comparison interventions will include the most common general practitioner management strategies for acute LBP, which will include medication or non-steroidal anti-inflammatory drugs (administered orally, via intramuscular injections, and topically), and advice7. Types of outcome measures: The outcomes of interest will include, but are not confined to: • Severity of pain (visual analogue scale) • Activity impairments (limitations in activities of daily living) and participation impairments (limitations in ability to work) as measured with standardized outcome measures. • Economic cost-effectiveness.