Despite much recent interest in the flipped classroom, quantitative studies are slowly emerging, particularly in the sciences. We report a year-long parallel controlled study of the flipped classroom in a second-term general chemistry course. The flipped course was piloted in the off-semester course in Fall 2014, and the availability of the flipped section in Spring 2015 was broadly advertised prior to registration. Students self-selected into the control and flipped sections, which were taught in parallel by the same instructor; initial populations were 206 in the control section, 117 in the flipped. As a pretest, we used the ACS first-term general chemistry exam (form 2005), given as the final exam across all sections of the first-term course. Analysis of pretest scores, student percentile rankings in the first-term course, and population demographics indicated very similar populations in the two sections. The course designs required comparable student effort, and five common exams were administered, in...