Women mental health and impact of psychosocial factors on it, is highlighted in various psychological & clinical studies, due to pandemic made it a matter of more focus. Studying the long-term impacts of the coronavirus on society, our mind, body and its analysis perhaps will take more time. Out of the total population, a number of people felt a disrupted sleep as a hallmark of the pandemic, and suffered from depression, insomnia, irritability, violence including domestic violence, distress, work pressure due to online culture of work, and other related negative mental health symptoms as idiosyncratic attributes especially in covid sufferers. Covid-19 pandemic has altered family dynamics. More screen time, unended & fluctuated routines, for working women dissolving boundaries in workplace and personal life altered & flicking habits, all impacted mental health adversely. The human brain is evolved to live in social groups & wired for social interactions, epidemiological studies conducted on covid survivors, convalescents & victims shows altered brain biochemistry due to various psychosocial factors including financial losses, social isolation, intimate partner’s negative mental state, discrimination, disrupted sleep & routines, etc. Pandemic might has altered the romantic and loving relationships, and adversity of such psychosocial factors impacted people. Psychological strengths and resilience mainly depend on social determinants like social support, social culture, respect, engagement at workplace, parenting style in childhood & emotional attachment, society & family bonds, self-regulation & behavior controlling, and collective efficacy, all these determinants are positively associated with self-esteem that have direct impact on enhancing psychological strengths. Population for the study as participants were females in early adulthood & studying, professional and housewives. For data analysis, the statistical tools, descriptive, co-relational and regression analysis is used. The study focuses on effect of adverse aspects of adversity like pandemics financial crises like job losses, allowances or salary deductions, led to economic abuses, and somewhere gender discrimination, sexual abuse, household workload, escalation in family members expectations and responsibilities, adverse impact of these psychosocial factors on women’s mental health and role of education, knowledge, skills, and aptitude i.e. abilities & cognitive competencies in coping and managing the adversities like pandemic.