Role Of Sex Research Articles

What is the role of sex and gender in the future of precision cardiology?

What is the role of sex and gender in the future of precision cardiology?

The Role of Sex in the Assessment of Return and Downside Risk in Decumulation Financial Planning

This paper aims to assess the return and downside risk of a decumulation portfolio established at the retirement age of a senior, with a determined lifetime horizon differentiated by the sex of the citizen. To measure the portfolio’s return and downside risk, two ratios conditioned by seniors’ risk attitude towards portfolio failure are employed: the downside Sortino ratio and the downside risk–return ratio. Unlike other research in the field, this manuscript provides three portfolio compositions catering to different senior investment profiles: aggressive, moderate, and conservative. Additionally, it offers a decumulation horizon conditioned by the sex-specific life expectancy of the individual, instead of offering different scenarios for conducting a sensitivity analysis. Lastly, this study was conducted across three socioeconomically distinct countries: the US, Spain, and Japan. The results clearly demonstrate that both sex and nationality significantly influence the selection of the optimal decumulation portfolio composition aimed at exhausting funds by the senior’s demise.

The role of sex and age in seasonal mortality – the case of Poland

The role of sex and age in seasonal mortality – the case of Poland

THE INFLUENCE OF SOCIAL MEDIA ON SOCIAL INTERACTIONS AMONG UNIVERSITY STUDENTS WITH FAMILY & SOCIAL CIRCLE

The current study aimed to investigate the effects of social media on social interactions among university students in KP with family and social circle. The objectives include, to examine the new pattern of social media for social relationship, association of gender communication pattern with family and social circle with respect to social interactions by using the survey research design. A sample of 900 students (270 male & 630 female) were selected over stratified sampling method. A questionnaire was used to collect the primary data. The descriptive statistics and inferential statistics were used for data analysis. The study concluded that majority of the male students frequently communicate with friend whereas female students sometime communicate with friends. Majority of male and female students frequently communicate with classmate. The majority of male and female students communicate with peers and never communicate with classmate. Majority of male and female students sometime communicate with religious scholar. Therefore, the study concluded that both male and female frequently interact through the social media with family and social circle but still physical interactions exist with in family.

The role of personal health beliefs and altruistic beliefs in young Chinese adult men’s acceptance of the human papillomavirus vaccine

Administering the human papillomavirus (HPV) vaccine to men offers substantial health benefits for both themselves and their female partners. In mainland China, the HPV vaccine has not been approved for men, and little is known about their acceptance of it. This study aims to assess the acceptability of HPV vaccine among young Chinese adult men and examine the association between personal health beliefs, altruistic beliefs, and HPV vaccination intentions and behavioral attempts. A cross-sectional study was conducted among male university students using a multistage cluster sampling method in eight universities across five districts in Zhejiang Province, China. Data were collected from December 2020 to January 2021 using a self-administered, anonymous online questionnaire. Of the 1937 participants, 1009 who had heard of the HPV vaccine completed the questionnaire. Over one-third (40.4%, 408/1009) had high levels of HPV and HPV vaccine knowledge. A total of 695 of 1009 (68.9%) expressed an intention to receive the HPV vaccine when available, and 329 of 1009 (32.6%) had proactively inquired about male HPV vaccination. Perceived susceptibility, perceived benefits, perceived gender barriers, and perceived benefits of male HPV vaccination for female partner were associated with HPV vaccination intentions. Lower perceived vaccine barriers, greater perceived benefits, and stronger vaccination intentions were associated with higher HPV behavioral attempts. There is an emerging demand for HPV vaccinations among young adult men in mainland China. Personal health beliefs and altruistic beliefs are crucial in promoting young adult men’s acceptance of the HPV vaccine. Emphasizing both male-specific benefits and altruistic motivations may enhance HPV vaccine acceptability among young adult men.

322.6: Delineating the role of biological sex in organ transplantation: Identifying estrogen receptor α enhanced 4-1BB signaling as a critical component of T cell-mediated alloimmunity.

322.6: Delineating the role of biological sex in organ transplantation: Identifying estrogen receptor α enhanced 4-1BB signaling as a critical component of T cell-mediated alloimmunity.

Reflective Practices A Comparative Analysis of Gender-based Differences and Barriers at Higher Secondary School Level

The gender differences and barriers to reflective practice have been compared in the present study. The study's main objectives were to observe the gender base differences in teachers about reflective practice and to check their views about barriers to following reflective practice. The nature of the following research was descriptive. This research paper sample consisted of 300 male and female teachers of higher secondary public and private schools. The collection of data was managed through a stratified random sampling technique. Inferential statistics were applied for the analysis of data. Gender base difference of opinions about reflective practice was discovered in this study as the female teachers showed more concern towards reflective practice as compared to their male colleagues. The results regarding the barriers to reflective practice were almost identical in public and private sector higher secondary schools. It was concluded that teachers of both the public and private sectors need professional training to apply reflective practices in classroom environments. It is suggested that technology can be applied in the teaching techniques which can be helpful to fulfill the present time needs.

Empowering Widowed Women with Sustainable Food Security in Tunyai Location, Tharaka Sub-County, Tharaka Nithi County, Kenya: A Qualitative Analysis of Their Roles, Challenges, and Resilience

Food security, a fundamental global concern, is intrinsically linked to the pivotal roles, women play in agricultural and food production. This qualitative research, conducted in Tunyai Location, Tharaka Sub-County, Tharaka Nithi County, Kenya, delves into the significant contributions of widowed women to food security by exploring their roles in agricultural and food production. The research aims to understand the experiences, challenges, and strategies of widowed women in enhancing the local food supply. Using a purposive sampling method, 50 widowed women actively engaged in agriculture were selected for participation in Key Informant Interviews. NVivo software facilitated the data analysis, enabling systematic exploration and thematic identification of patterns, challenges, and strategies employed by these women. The study findings underscore the profound contributions of widowed women to food security, with 56% actively engaged in agricultural activities. These women represent a cornerstone in sustaining local food security through diverse roles encompassing crop cultivation, livestock management, and food processing. Furthermore, the research underscores the need to address the 44% of widowed women not actively involved, emphasizing potential gender disparities and barriers. In conclusion, this study highlights the integral role of women in enhancing food security and the imperative to address gender-related challenges to ensure a resilient and sustainable local food supply in Tunyai Location.

Game talk: exploring the linguistic features of sports commentary

This study is investigating the linguistic features of sports commentary. The focus is the politeness techniques using and gender-specific language variations observed in 2022 FIFA World Cup. This study used qualitative approach. This study was examining the collection of real-time commentary from various matches in 2022 World Cup. The analysis of this study focusses on prominent politeness methods, including softened criticism, neutral descriptions, respectful acknowledgments, and positive reinforcement. It further investigates the effectiveness of these strategies in the specific context of live sports broadcasting. The findings suggest that the use of politeness tactics is important for maintaining the professional users and engaging tone when commenting the match. This study also found that female commentators disposed to use more supportive and cooperative language, emphasizing teamwork and exertion, while male commentators disposed to use more competitive and authoritative language, focusing on individual performance and strategic analysis. These findings consistent with the research on gender communication and emphasize the significance of comprehending special style communication styles in sports commentary. This study branch holds significant importance for both the field of sports broadcasting and the branch of linguistics. The results indicate that commentator training programs should include knowledge of politeness techniques and gender-specific communication styles in order to improve audience involvement and provide a pleasant viewing experience. This work improves the knowledge of language usage in real-time sports commentary, such as dynamic and culturally significant situation in linguistic form. It highlights the significance of language in reflect and reinforce the cultural values and conventions, promoting inclusiveness, and deepening the spectator’s which tie up with the event. Keywords: Live Sports Commentary, Politeness Strategies, Sports Broadcasting.

Association of sex with in-hospital management and outcomes of patients with heart failure: Data from the REAL-HF registry

BackgroundThere are sex differences in HF patients. It is not clear whether such differences mainly reflect cultural behaviours and clinical inertia, and the role of sex on clinical outcomes is still controversial. We aimed to investigate the association of sex with in-hospital management and outcomes in patients with HF. MethodsWe analyzed data of 4016 adult patients hospitalized for HF in 2020-2021 and enrolled in a multicentre national registry. ResultsWomen (n=1818[45%]) were older than men (83vs77 years, p<0.0001), with a higher prevalence of arterial hypertension (73%vs69%, p=0.011) and atrial fibrillation. Women presented more frequently with HF and preserved ejection fraction -HFpEF (55%vs32%, p<0.001). They were more often hospitalized in internal medicine departments (71%vs51%), and men in highly specialized cardiology units (49%vs29%). When considering HF pharmacological treatments at discharge in the subgroup with reduced ejection fraction -HFrEF (n=1525), there were no significant differences (49% of women treated with GDMT [guideline-directed medical therapy] vs 52% of men, p=0.197). Sex was not associated either with hospital readmissions (30-days OR[95%CI]=0.89[0.71-1.11], p=0.304; 1-year OR[95%CI]=1.02[0.88-1.19], p=0.777) or with mortality (in-hospital OR[95%CI]=1.14[0.73-1.78], p=0.558; 1-year OR[95%CI]=1.08[0.87-1.33], p=0.478). Similar results were obtained when considering different HF categories based on left ventricular ejection fraction. ConclusionsWomen and men exhibited distinct clinical profiles. Although this may have had an impact on hospital pathways (non-cardiology/cardiology units) and pharmacological prescriptions, sex per se did not appear as an independent determinant of clinical choices. Moreover, when considering homogeneous groups, women were not undertreated. Finally, female sex was not associated with worse clinical outcomes.

The role of sex and age in the differential efficacy of 10 Hz and intermittent theta-burst (iTBS) repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD)

BackgroundSex- and age-dependent outcome differences have been observed in treatment of Major Depressive Disorder (MDD), including 10 Hz repetitive Transcranial Magnetic Stimulation (rTMS). We examined whether there are sex- and age-dependent differences in outcome with intermittent Theta Burst Stimulation (iTBS), another rTMS protocol. MethodsThe relationship between biological sex, age, and treatment outcome was retrospectively examined among 414 patients with MDD treated with 10 Hz or iTBS rTMS. Linear mixed-effects modeling was used to examine the association between treatment and change in the 30-item Inventory of Depressive Symptomatology Self-Report (IDS-SR30) score from baseline to treatments 10 and 30, with biological sex (M/F), protocol (iTBS/10 Hz), age (≥/<50 years old), and time (treatment 1/10/30) included as fixed effects. The three-way sex-protocol-time and age-protocol-time interactions were used to determine any differential relationships between protocol and outcome dependent on sex and age. Post-hoc t-tests were conducted to examine differences in improvement. ResultsThere was a significant three-way sex-protocol-time interaction at treatments 10 (p = 0.016) and 30 (p = 0.031). Males showed significantly greater improvement with iTBS than females at treatments 10 (p = 0.041) and 30 (p = 0.035), while females showed numerically greater improvement with 10 Hz treatment. While there was not a significant three-way age-protocol-time interaction, there was a significant interaction between age (≥50 years old) and time at treatments 10 (p = 0.007) and 30 (p = 0.042), and among age, sex, and time at treatment 30 (p = 0.028). LimitationsRetrospective naturalistic treatment protocol. ConclusionsiTBS appeared less efficacious in females than in males, and rTMS overall was more efficacious in patients over fifty, particularly females.

Perception of Health Risks of Electronic Cigarette Use Among College Students: Examining the Roles of Sex, Field of Study, Vaping Device Type, and Their Associations.

Electronic cigarettes are marketed as a safer alternative to regular (combustible) cigarettes, based on the claim that there is no tobacco burning and fewer toxic chemicals in their vapor. However, recent evidence challenges the notion that e-cigarette aerosols are benign. Heating of compounds in e-liquids to high temperatures can lead to the release of toxic compounds in e-cigarette aerosols. However, users and the public may not be aware of these unique harms, impacting their perception of harm from using e-cigarettes. This research explored the perceptions of harm of e-cigarettes compared to regular cigarettes among 418 college students, aged 18-34, by employing a Qualtrics based smartphone survey. The findings revealed a vaping prevalence of 16.7% among our study population, indicating e-cigarette use among college aged young adults is at concerning levels. Perceptions of harm varied significantly by vaping status, sex, and field of study. Non-e-cigarette users and female students were less likely to perceive e-cigarettes as less harmful than regular cigarettes. Among e-cigarette users (vapers), male vapers and users of pod-type devices, such as JUUL and disposables, were more inclined to view e-cigarettes as less harmful. Among vapers, students in non-health-related fields were significantly more likely to perceive e-cigarettes as less harmful than regular cigarettes, underscoring the impact of educational background on health risk awareness. In conclusion, this study provides crucial insights into the varied perceptions of e-cigarettes among young adults. The results emphasize the need for targeted public health interventions and educational efforts to address this growing public health concern.

Attentional bias to alcohol-related cues: effects of menstrual cycle phase and sex differences.

A recent study by our group found that women displayed greater attentional bias to alcohol-related cues during the late versus early follicular phase in both sober and intoxicated states, suggesting a greater risk of excessive drinking among women during this phase. Changes in attentional bias as a function of menstrual cycle phase raise questions about potential sex differences in the relative consistency by which women and men display attentional bias to alcohol over time. The present study tested sex differences in attentional bias to alcohol by comparing the change in women's attentional bias from early to late follicular phase to that observed in men over the same period. Twenty-five men and 25 women aged 21-32 participated in a placebo-controlled study examining sex differences in the rewarding properties of alcohol. Participants completed measures of attentional bias to alcohol-related cues during two sessions following both 0.6g/kg alcohol and placebo. Test sessions occurred one week apart, and for female participants coincided with the early and late follicular phases. Men consistently displayed attentional bias to alcohol-related cues across sessions under both doses. By contrast, women showed attentional bias only during the late follicular phase, at a magnitude greater than that observed in men, and persistent under both doses. These findings highlight the potential role of sex and menstrual cycle phase in sensitizing drinkers to rewarding properties of alcohol-related cues. Men's motivation to drink may remain relatively consistent, whereas women may be most motivated during the late follicular phase.

Addressing Health Illiteracy and Stunting in Culture-Shocked Indigenous Populations: A Case Study of Outer Baduy in Indonesia.

This research aims to determine the factors, impacts, and solutions for health literacy in the Outer Baduy hamlets of Kanekes Village, Indonesia. The method used in this research is qualitative, which produces an in-depth explanation of the existing problems. Data were collected through interviews and documentation. Interviews were conducted with key figures, including two female Baduy residents with stunted children, one retainer, the head of the NGO SRI, a midwife who works in the Baduy village, and the head of the Lebak social service. Apart from that, secondary data in the form of recordings of community service talk shows conducted by the University of Indonesia to overcome stunting in Baduy were also analysed. The results show that the factors associated with the low health literacy of the Baduy community are literacy, writing and reading, taboos on eating certain foods, people spending too much time in the fields, people learning by imitating their parents, demanding access to villages, lack of consistency from external parties in providing health programs, and gender segregation in Baduy society. The impact of the low health literacy of the Baduy community is fatalism, high maternal and child mortality rates, and high health costs. The proposed strategies for increasing the health literacy of the Baduy community based on the findings of this research include developing health literacy by targeting community leaders, managing information-technology-based health-information groups, and always presenting at least one health worker among the residents who provides an example of healthy living, encouraging collective reflection. when health cases occur, and balancing gender communication.

The Role of Sex and Gender in Transgender Bone and Other Musculoskeletal Health.

Musculoskeletal changes occur with gender-affirming hormonal therapy (GAHT) and gender-affirming surgery (GAS) used in the care of transgender adolescents and adults. Survey results have shown that orthopaedic surgeons desire to care for transgender individuals but express concern over a knowledge deficit. This article reviews the physiology and pathophysiology that may occur with GAHT and GAS. Transgender women have lower bone mineral density (BMD) prior to GAHT than cisgender men. Limited fracture data would suggest that transgender women >50 years of age have fracture rates similar to those of cisgender women. Transgender men have normal BMD prior to GAHT and are not at an increased risk for fracture compared with cisgender women. The use of puberty-blocking medications in the care of transgender youth does result in a decline in BMD, which returns to baseline with GAHT, but the effect of delaying puberty on maximal BMD and the lifetime fracture risk are unknown. At present, dual x-ray absorptiometry (DXA) is used to measure BMD and assess fracture risk. Attention should be paid to using the appropriate reference group in the interpretation of DXA for transgender individuals. Promote musculoskeletal health by ensuring appropriate calcium, vitamin D, weight-bearing activity, and a healthy lifestyle. Adherence to GAHT needs to be encouraged to avoid bone loss. Data with regard to therapy for osteoporosis in transgender patients have been lacking, but, at present, use of available therapies is expected to be effective. Information with regard to differences in other musculoskeletal health issues such as joint injuries has been lacking in transgender individuals.

Cultural values in Colombia and Chile: The role of sex

Cultural values in Colombia and Chile: The role of sex

Sex differences in survival following surgery for esophageal cancer: A systematic review and meta-analysis.

The impact of sex on the prognosis of patients with esophageal cancer remains unclear. Evidence supports that sex- based disparities in esophageal cancer survival could be attributed to sex- specific risk exposures, such as age at diagnosis, race, socioeconomic status, smoking, drinking, and histological type. The aim of our study is to investigate the role of sex disparities in survival of patients who underwent surgery for esophageal cancer. A systematic review and meta-analysis of the existing literature in PubMed, EMBASE, and CENTRAL from December 1966 to February 2023, was held. Studies that reported sex-related differences in survival outcomes of patients who underwent esophagectomy for esophageal cancer were identified. A total of 314 studies were included in the quantitative analysis. Statistically significant results derived from 1-year and 2-year overall survival pooled analysis with Relative Risk (RR) 0.93 (95% Confidence Interval (CI): 0.90-0.97, I2= 52.00) and 0.90 (95% CI: 0.85-0.95, I2= 0.00), respectively (RR < 1 = favorable for men). In the postoperative complications analysis, statistically significant results concerned anastomotic leak and heart complications, RR: 1.08 (95% CI: 1.01-1.16) and 0.62 (95% CI: 0.52-0.75), respectively. Subgroup analysis was performed among studies with <200 and > 200 patients, histology types, study continent and publication year. Overall, sex tends to be an independent prognostic factor for esophageal carcinoma. However, unanimous results seem rather obscure when multivariable analysis and subgroup analysis occurred. More prospective studies and gender-specific protocols should be conducted to better understand the modifying role of sex in esophageal cancer prognosis.

Religiosity’s Links to Adolescent Wellbeing and the Role of Supportive Networks and Sex

Research has extensively examined religiosity’s links to youth wellbeing, but it is unclear how the relationship may vary by supportive networks and sex. Analyzing data from the 2015 to 2020 National Survey on Drug Use and Health, the results showed that religious salience was negatively associated with the risk of having a past-year major depressive episode (MDE, OR = 0.65), a substance use disorder ( OR = 0.77), and delinquency ( OR = 0.94). Supportive networks also indicated similar associations. Furthermore, supportive networks and sex appeared to moderate religious salience’s links to having an MDE and delinquency in some aspects. The study concludes that religious salience appears to be a protective factor for adolescents’ mental and behavioral wellbeing, though some of its impact may vary by sex and supportive networks. The findings advance the understanding of religiosity’s role in adolescents’ wellbeing and suggest considering tailored plans for optimized outcomes.

Tradisi VS Modernitas: Konflik Generasi dan Komunikasi Gender dalam Crashing Eid

This study investigates the intricate dynamics of tradition versus modernity through the lens of generational conflict and gender communication in the Netflix series "Crashing Eid." Utilizing a systematic content analysis, the research aims to identify and categorize representations of these themes within the series. The analysis focuses on key aspects such as traditional versus modern values, generational perspectives, and gender roles as depicted in the interactions and dialogues of the characters. The findings reveal that "Crashing Eid" effectively portrays the tension between traditional and modern values, particularly in the context of family expectations and personal aspirations. The series highlights the challenges faced by younger generations in balancing respect for cultural heritage with the desire for individual autonomy. Gender communication is intricately woven into these narratives, showcasing the evolving roles of women and men within the Saudi Arabian cultural setting. The study underscores the importance of media representation in reflecting and shaping societal norms and values. "Crashing Eid" serves as a poignant example of how contemporary media can address and bring to light the complexities of generational and gender-related conflicts. The research contributes to the broader discourse on cultural change and continuity, emphasizing the role of media in facilitating dialogue and understanding across different societal segments.

Role of age and sex in the incidence of adverse effects among diabetic patients treated with glipizide.

Glipizide is an antidiabetic drug that belongs to a class of medication known as sulfonylureas. It is considered one of the highly prescribed antidiabetic drugs for the treatment of type II diabetes in patients following a kidney transplant. It lowers blood glucose levels by causing the release of insulin from β-cells in the pancreas. Its main metabolizing pathway is through the liver. It has several adverse effects, which range from an upset stomach to glipizide-induced haemolytic anaemia and hypoglycaemia. These adverse effects may be spontaneous, or they could have a genetic cause. The present study aimed to assess and document the incidence of glipizide-induced adverse reactions among patients prescribed the drug. The present retrospective case-control study used the electronic medical records of patients prescribed glipizide for the past 3 years. These records were reviewed to extract and document cases and/or signs of glipizide-induced adverse reactions. The results revealed that the incidence of adverse effects was higher among female patients (odds ratio, 2.40, P<0.001). Moreover, the results revealed that the likelihood of developing adverse drug reactions among patients <40 years of age was higher than in older patients (P>0.05). The outcomes of the present study are expected to prompt future studies to take sex and age into consideration, in an aim to improve treatment outcomes, reduce adverse events and decrease the burden of unnecessary costs for healthcare systems. Recommendations also include genetic screening prior to administering the medication, educating the patients and caregivers on the possibility of adverse drug reactions, and routine follow-up. This issue is of utmost importance to achieve the optimal outcomes with the minimal detrimental effects.