This study examines the economic impact of the One District One Product (ODOP) scheme on state-level GDP growth in India using time-series econometric models from 2011 to 2023. The ODOP initiative, launched by the Indian government, aims to promote regional economic development by fostering unique local products from each district. By employing Vector Autoregression (VAR) and Johansen Co-Integration methods, the research quantitatively assesses the causal relationship between the ODOP scheme and GDP growth across various states. Preliminary findings suggest that ODOP significantly contributes to regional GDP, particularly through enhancing local production and market reach, thereby integrating regional economies into national and global value chains. This study underscores the importance of targeted regional policies in achieving broader economic objectives and fostering sustainable development. It also highlights the ODOP scheme’s role in promoting traditional products and skills, which aligns with the government's larger goals of a self-reliant India.